NIBR189

Base Information

Chemical Name:NIBR189
CAS No.:1599432-08-2
Molecular Formula:C₂₁H₂₁BrN₂O₃
Molecular Weight:429.313
Hs Code.:
Mol file:1599432-08-2.mol

Synonyms:(2E)-3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one

Suppliers and Price of NIBR189

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
NIBR 189
10mg
$ 438.00

TRC
(2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one
100mg
$ 1105.00

Tocris
NIBR189 ≥99%(HPLC)
10
$ 193.00

Tocris
NIBR189 ≥99%(HPLC)
50
$ 789.00

DC Chemicals
NIBR189 >98%
100 mg
$ 450.00

Crysdot
NIBR189 98+%
10mg
$ 350.00

Crysdot
NIBR189 98+%
5mg
$ 245.00

Crysdot
NIBR189 98+%
50mg
$ 1050.00

Crysdot
NIBR189 98+%
100mg
$ 1470.00

ChemScene
NIBR189 ≥99.0%
100mg
$ 2520.00

Total 15 raw suppliers

Chemical Property of NIBR189

Chemical Property:

Boiling Point:639.7±55.0 °C(Predicted)
PKA:-0.86±0.70(Predicted)
Density:1.403±0.06 g/cm3(Predicted)
Solubility.:≥42.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

Purity/Quality:

99%, ^*data from raw suppliers

NIBR 189 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases.

Technology Process of NIBR189

There total 1 articles about NIBR189 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1200-07-3,5676-63-1,17916-60-8
trans-4-bromocinnamic acid

: 94747-49-6
(4?methoxyphenyl)(piperazin?1?yl)methanone

: 1599432-08-2
(2E)-3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one

Guidance literature:: With 4-methyl-morpholine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm4019355