(R)-2-AMINO-1-(FURAN-2-YL)-ETHANOL

Base Information

• Chemical Name: (R)-2-AMINO-1-(FURAN-2-YL)-ETHANOL
• CAS No.: 139683-93-5
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127.143
• Hs Code.: 2932190090
• Mol file: 139683-93-5.mol

Synonyms:2-Furanmethanol,a-(aminomethyl)-, (R)-;(R)-2-Amino-1-(2-furyl)ethanol; (R)-2-Amino-1-(2-furyl)ethanol; (R)-a-(Aminomethyl)-2-furanmethanol

Chemical Property of (R)-2-AMINO-1-(FURAN-2-YL)-ETHANOL

Chemical Property:

• PSA: 59.39000
• LogP: 0.97200

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-AMINO-1-(FURAN-2-YL)ETHANOL 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-2-AMINO-1-(FURAN-2-YL)-ETHANOL

There total 7 articles about (R)-2-AMINO-1-(FURAN-2-YL)-ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(R)-[2-azido-1-(furan-2-yl)ethoxy](tert-bityl)dimethylsilane (1007402-77-8) → (R)-2-amino-1-(furan-2-yl)ethanol (139683-93-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

DOI:10.1016/j.tetasy.2007.11.034

Reference yield: 64.0%

(R)-(-)-2-(2-furyl)-2-hydroxyacetonitrile (121986-08-1) → (R)-2-amino-1-(furan-2-yl)ethanol (139683-93-5)

Guidance literature:

With sodium tetrahydroborate; trifluoroacetic acid; In tetrahydrofuran; at 15 - 25 ℃; Inert atmosphere;

DOI:10.1021/op050264b

Reference yield: 38.0%

(1R)-2-azido-1-(2-furyl)ethan-1-ol → (R)-2-amino-1-(furan-2-yl)ethanol (139683-93-5)

Guidance literature:

With hydrogen; sodium hydroxide; In aq. phosphate buffer; water; at 30 ℃; for 4h; under 7500.75 Torr; pH=9; Green chemistry;

DOI:10.1039/c3gc41666f

upstream raw materials:

(R)-[2-azido-1-(furan-2-yl)ethoxy](tert-bityl)dimethylsilane

furfural

(R)-(-)-2-(2-furyl)-2-hydroxyacetonitrile

2-azido-1-(furan-2-yl)-ethanone

Downstream raw materials:

N-(4-chlorobenzyl)-2-((((2R)-2-(2-furyl)-2-hydroxyethyl)(methyl)amino)methyl)-4-oxo-7-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

N-(4-chlorobenzyl)-7-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-2-((((2R)-2-(2-furyl)-2-hydroxyethyl)(methyl)amino)methyl)-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

N-(4-chlorobenzyl)-2-((((2R)-2-(2-furyl)-2-hydroxyethyl)(methyl)amino)methyl)-4-oxo-7-(3-(tetrahydro-2H-pyran-2-yloxy)propyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

N-(4-chlorobenzyl)-2-((((2R)-2-(2-furyl)-2-hydroxyethyl)(methyl)amino)methyl)-4-oxo-7-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide

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