methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Base Information

Chemical Name:methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate
CAS No.:441778-48-9
Molecular Formula:C₃₄H₄₁NO₈
Molecular Weight:591.701
Hs Code.:

Synonyms:methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Suppliers and Price of methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

There total 10 articles about methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58632-95-4
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

: (2R,3R,4S,5R,6S)-5-Amino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-carboxylic acid methyl ester

: 441778-48-9
methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Guidance literature:: With triethylamine; In methanol; at 20 ℃; for 12h;
DOI:10.1016/S0968-0896(02)00020-2

Reference yield:

: 57039-37-9
(2R,3R,45,5R,6R)-methyl 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-carboxylate

: 441778-48-9
methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Guidance literature:: Multi-step reaction with 7 steps

1.1: 61 percent / HCO₂H / 1 h / 20 °C

2.1: NaH / dimethylformamide / 12 h / 20 °C

2.2: 93 percent / methanol / 2 h / 20 °C / pH 11

3.1: 94 percent / HCl; NaBH₃CN; 3 Angstroem molecular sieves / ethyl acetate; tetrahydrofuran / 0.33 h / 20 °C

4.1: pyridine / CH₂Cl₂ / 2 h / -15 °C

5.1: 1.20 g / NaN₃ / dimethylformamide / 12 h / 20 °C

6.1: H₂S / pyridine; H₂O / 1 h / 20 °C

7.1: 1.31 g / Et₃N / methanol / 12 h / 20 °C

With pyridine; hydrogenchloride; formic acid; sodium azide; 3 A molecular sieve; hydrogen sulfide; sodium hydride; sodium cyanoborohydride; triethylamine; In tetrahydrofuran; pyridine; methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(02)00020-2

Reference yield:

: 197720-07-3
methyl 2,6-anhydro-3,4,7-tri-O-benzyl-D-glycero-L-manno-hepturonate

: 441778-48-9
methyl 2,6-anhydro-3,4,7-tri-O-benzyl-5-tert-butoxycarbonylamido-5-deoxy-D-glycero-D-gulo-hepturonate

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / CH₂Cl₂ / 2 h / -15 °C

2: 1.20 g / NaN₃ / dimethylformamide / 12 h / 20 °C

3: H₂S / pyridine; H₂O / 1 h / 20 °C

4: 1.31 g / Et₃N / methanol / 12 h / 20 °C

With pyridine; sodium azide; hydrogen sulfide; triethylamine; In pyridine; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(02)00020-2