(-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione

Base Information

• Chemical Name: (-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione
• CAS No.: 1307800-88-9
• Molecular Formula: C₁₉H₁₈N₂S₂
• Molecular Weight: 338.497
• Mol file: 1307800-88-9.mol

Synonyms:(-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione

Chemical Property of (-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione

There total 1 articles about (-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

carbon disulfide (75-15-0,12122-00-8) + (2S)-2-(benzylamino)-3-(1H-indol-3-yl)propan-1-ol → (-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione (1307800-88-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 25 ℃; for 15h; Inert atmosphere;

DOI:10.1002/chem.201001735

Reference yield: 61.0%

(-)-(S)-3-benzyl-4-[(1H-indol-3-yl)methyl]-1,3-thiazolidine-2-thione (1307800-88-9) → 3-allylindole (16886-09-2)

Guidance literature:

With 2-(trimethylsilyl)phenyl trifluoromethanesulfonate; cesium fluoride; In acetonitrile; at 20 ℃; for 4.5h; Inert atmosphere;

DOI:10.1002/chem.201001735

upstream raw materials:

carbon disulfide

Downstream raw materials:

3-allylindole