N-ethyl-4-thiocyanatobenzenamine

Base Information

• Chemical Name: N-ethyl-4-thiocyanatobenzenamine
• CAS No.: 33192-09-5
• Molecular Formula: C₉H₁₀N₂S
• Molecular Weight: 178.258
• Mol file: 33192-09-5.mol

Synonyms:N-ethyl-4-thiocyanatobenzenamine

Chemical Property of N-ethyl-4-thiocyanatobenzenamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-ethyl-4-thiocyanatobenzenamine

There total 11 articles about N-ethyl-4-thiocyanatobenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ammonium thiocyanate (1147550-11-5) + N-ethyl-N-phenylamine (103-69-5) → N-ethyl-4-thiocyanatobenzenamine (33192-09-5)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In acetonitrile; at 20 ℃; for 0.166667h;

DOI:10.1055/s-0028-1083636

Reference yield: 90.0%

CNPolS + N-ethyl-N-phenylamine (103-69-5) → N-ethyl-4-thiocyanatobenzenamine (33192-09-5)

Guidance literature:

With dipotassium peroxodisulfate; In ethanol; water; at 55 ℃; for 0.166667h; poly(4-vinylpyridine) cross-linked with 2percent divinyl benzene regioselective reaction; Green chemistry;

DOI:10.1080/17415993.2014.917375

Reference yield: 88.0%

N-ethyl-N-phenylamine (103-69-5) → N-ethyl-4-thiocyanatobenzenamine (33192-09-5)

Guidance literature:

With Oxone; In methanol; at 20 ℃; for 0.333333h; regioselective reaction; Green chemistry;

DOI:10.1080/10426507.2013.865123

upstream raw materials:

phenethylamine

1-methyl-3-phenyl-2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl thiocyanate

ammonium thiocyanate

N-ethyl-N-phenylamine

Downstream raw materials:

2,3-difluorobenzonitrile

N-Aethoxycarbonylmethyl-N'-aethyl-N'-(4-thiocyanato-phenyl)-harnstoff

Refernces

• 1、 Yadav,Reddy, B. V. Subba,Reddy, Y. Jayasudhan. "1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2,2,2]octane Bis(tetrafluoroborate) as Novel and Versatile Reagent for the Rapid Thiocyanation of Indoles, Azaindole, and Carbazole". . p. 652 - 653. Retrieved 2008.
• 2、 Zhang, Pengfei,Yin, Yucheng,Wang, Zhengxin,Yu, Chunyang,Zhu, Yizhou,Yan, Deyue,Liu, Weimin,Mai, Yiyong. "Porphyrin-Based Conjugated Microporous Polymer Tubes: Template-Free Synthesis and A Photocatalyst for Visible-Light-Driven Thiocyanation of Anilines". . p. 3543 - 3553. Retrieved 2021/04/12.
• 3、 Yi, Bing,Wen, Xiaoyong,Yi, Ziqi,Xie, Yanjun,Wang, Qiang,Tan, Jian-Ping. "Visible-light-enabled regioselective aerobic oxidative C(sp2)-H thiocyanation of aromatic compounds by Eosin-Y photocatalyst". supporting information. . Retrieved 2020/11/19.