tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Base Information

Chemical Name:tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate
CAS No.:1349842-35-8
Molecular Formula:C₂₀H₃₄O₅Si₂
Molecular Weight:410.658
Hs Code.:

Synonyms:tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Suppliers and Price of tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

There total 4 articles about tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 40052-13-9
mono-tert-butyl malonate

: 1349842-32-5
4-hydroxy-4-methyl-2,6-bis(trimethylsilyl)cyclohexa-2,5-dienone

: 1349842-35-8
tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; Inert atmosphere;
DOI:10.1039/c1ob06125a

Reference yield:

: 154345-34-3
2-bromo-4-methyl-6-(trimethylsilyl)phenol

: 1349842-35-8
tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / toluene / 12 h / Reflux

2: n-butyllithium / tetrahydrofuran; hexane / -100 - -50 °C

3: [bis(acetoxy)iodo]benzene / water; acetonitrile / 0 °C

4: dmap; dicyclohexyl-carbodiimide / dichloromethane / Inert atmosphere

With dmap; n-butyllithium; [bis(acetoxy)iodo]benzene; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; hexane; dichloromethane; water; toluene; acetonitrile;
DOI:10.1039/c1ob06125a

Reference yield:

: 1313182-64-7
trimethylsilyl 2-bromo-4-methyl-6-(trimethylsilyl)phenyl ether

: 1349842-35-8
tert-butyl (1-methyl-4-oxo-3,5-bis(trimethylsilyl)cyclohexa-2,5-dien-1-yl) malonate

Guidance literature:: Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran; hexane / -100 - -50 °C

2: [bis(acetoxy)iodo]benzene / water; acetonitrile / 0 °C

3: dmap; dicyclohexyl-carbodiimide / dichloromethane / Inert atmosphere

With dmap; n-butyllithium; [bis(acetoxy)iodo]benzene; dicyclohexyl-carbodiimide; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
DOI:10.1039/c1ob06125a