Technology Process of C18H20O4
There total 10 articles about C18H20O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C22H28O5;
With
diisobutylaluminium hydride;
In
dichloromethane; toluene;
at -78 ℃;
for 1.41667h;
Inert atmosphere;
With
rochelle salt;
In
dichloromethane; water; toluene;
at -78 - 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ja411270d
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: trifluoroacetic acid / chloroform / 20 °C / Inert atmosphere
2.1: 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate / acetonitrile / 1 h / 0 °C / Molecular sieve; Inert atmosphere
3.1: tetrabutyl ammonium fluoride; acetic acid / dichloromethane; tetrahydrofuran / 14 h / 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran; hexane / 0.58 h / 0 - 20 °C / Inert atmosphere
4.2: 18 h / 55 °C / Inert atmosphere
5.1: diisobutylaluminium hydride / dichloromethane; toluene / 1.42 h / -78 °C / Inert atmosphere
5.2: 2 h / -78 - 20 °C / Inert atmosphere
With
tetrapropylammonium perruthennate; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; acetic acid; 4-methylmorpholine N-oxide; trifluoroacetic acid;
In
tetrahydrofuran; hexane; dichloromethane; chloroform; toluene; acetonitrile;
4.1: |Horner-Wadsworth-Emmons Olefination / 4.2: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ja411270d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrabutyl ammonium fluoride; acetic acid / dichloromethane; tetrahydrofuran / 14 h / 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; hexane / 0.58 h / 0 - 20 °C / Inert atmosphere
2.2: 18 h / 55 °C / Inert atmosphere
3.1: diisobutylaluminium hydride / dichloromethane; toluene / 1.42 h / -78 °C / Inert atmosphere
3.2: 2 h / -78 - 20 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; acetic acid;
In
tetrahydrofuran; hexane; dichloromethane; toluene;
2.1: |Horner-Wadsworth-Emmons Olefination / 2.2: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ja411270d
