(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate
CAS No.:947739-49-3
Molecular Formula:C₂₇H₄₀N₆O₆S
Molecular Weight:576.717
Hs Code.:

Synonyms:(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Suppliers and Price of (S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

There total 4 articles about (S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 947739-48-2
(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(N-(methylsulfonyl)-methylsulfonamido)pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

: 947739-49-3
(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Guidance literature:: With water; potassium carbonate; In tetrahydrofuran; methanol; at 40 ℃; for 96h;

Reference yield:

: 630123-60-3
N-(2-[N',N'-diethylamino]-5-aminopyrimidin-4-yl)-4'-(pyrrolidin-1-ylcarbonyloxy)-L-phenylalanine tert-butyl ester

: 947739-49-3
(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran; dichloromethane / 18 h / 0 - 20 °C

2: water; potassium carbonate / tetrahydrofuran; methanol / 96 h / 40 °C

With water; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 630123-58-9
N-(2-[N',N'-diethylamino]-5-nitropyrimidin-4-yl)-4'-(pyrrolidin-1-ylcarbonyloxy)-L-phenylalanine tert-butyl ester

: 947739-49-3
(S)-4-(3-tert-butoxy-2-(2-(diethylamino)-5-(methylsulfonamido)-pyrimidin-4-ylamino)-3-oxopropyl)phenyl pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

2: triethylamine / tetrahydrofuran; dichloromethane / 18 h / 0 - 20 °C

3: water; potassium carbonate / tetrahydrofuran; methanol / 96 h / 40 °C

With water; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane;