N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Base Information

Chemical Name:N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester
CAS No.:80954-43-4
Molecular Formula:C₃₈H₅₃N₃O₁₀
Molecular Weight:711.853
Hs Code.:

Synonyms:N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Suppliers and Price of N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

There total 1 articles about N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 60686-50-2,60686-52-4
N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamic acid

: 78746-71-1
L-alanyl-L-leucine benzyl ester trifluoroacetate

: 80954-43-4
N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In acetonitrile; at 0 ℃; for 75h;
DOI:10.1021/jo00349a003

Reference yield: 69.0%

: 80954-43-4
N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

: 80954-40-1
N-(benzyloxycarbonyl)-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

Guidance literature:: With trifluoroacetic acid; at 0 ℃; for 2h;
DOI:10.1021/jo00349a003

Reference yield:

: 80954-43-4
N-(benzyloxycarbonyl)-γ,γ-di-tert-butyl-L-γ-carboxyglutamyl-L-alanyl-L-leucine benzyl ester

: 80954-42-3
N-(benzyloxycarbonyl)-L-γ-methyleneglutamyl-L-alanyl-L-leucine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / aq. trifluoroacetic acid / 2 h / 0 °C

2: 80 percent / dimethylamine / H₂O; propan-2-ol; acetonitrile / 20 h / Ambient temperature

With dimethyl amine; trifluoroacetic acid; In water; isopropyl alcohol; acetonitrile;
DOI:10.1021/jo00349a003