((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone

Base Information

• Chemical Name: ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone
• CAS No.: 163779-33-7
• Molecular Formula: C₃₆H₄₈O₁₀S₂
• Molecular Weight: 704.903
• Mol file: 163779-33-7.mol

Synonyms:((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone

Chemical Property of ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone

There total 1 articles about ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5R)-(L-menthyloxy)-2(5H)-furanone (112968-75-9,122079-41-8,122079-45-2,135041-07-5,77934-87-3) + 3,4,5-trimethoxy-benzaldehyde (86-81-7) + 1,2-(methylenedioxy)-3-methoxy-4-<(1,3-propylenedithio)methyl>benzene (163779-32-6) → ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone (163779-33-7)

Guidance literature:

With n-butyllithium; chlorotitanium tris(diethylamide); Yield given. Multistep reaction;

DOI:10.1021/jm00012a010

Reference yield: 90.0%

ethyl vinyl ether (109-92-2,25104-37-4) + ((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone (163779-33-7) → ((3R,4R,5R)7αR)-3-<(3,4,5-trimethoxyphenyl)<(ethoxyethyl)oxy>methyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5(1-methyloxy)dihydro-2(3H)-furanone

Guidance literature:

With o-toluenesulfonic acid; In tetrahydrofuran; for 1h;

DOI:10.1021/jm00012a010

Reference yield: 67.0%

((3R,4R,5R)7αR)-3<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>(1,3-propylenedithio)methyl>-5-(1-methyloxy)dihydro-2(3H)-furanone (163779-33-7) → ((3R,4R,5R)7αR)-3-<(3,4,5-trimethoxyphenyl)hydroxymethyl>-4-<<2-methoxy-3,4-(methylenedioxy)phenyl>oxomethyl>-5-(1-menthyloxy)dihydro-2(3H)-furanone

Guidance literature:

With calcium carbonate; mercury dichloride; In water; acetone; acetonitrile; for 0.5h;

DOI:10.1021/jm00012a010

upstream raw materials:

(5R)-(L-menthyloxy)-2(5H)-furanone

3,4,5-trimethoxy-benzaldehyde

1,2-(methylenedioxy)-3-methoxy-4-<(1,3-propylenedithio)methyl>benzene