N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Base Information

Chemical Name:N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
CAS No.:140712-80-7
Molecular Formula:C37H35 N3 O7
Molecular Weight:633.701
Hs Code.:
DSSTox Substance ID:DTXSID401165128
Nikkaji Number:J1.176.327H
Mol file:140712-80-7.mol

Synonyms:140712-80-7;N4-BENZOYL-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYCYTIDINE;Cytidine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-;N-(1-((2R,4S,5R)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide;N-[1-[(2R,4S,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide;N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine;SCHEMBL6930827;PTIHHTLJYOOJIY-VOTWKOMSSA-N;DTXSID401165128;MFCD04972285;AKOS030241096;F90238;N4-benzoyl-3'-O-(4, 4'-dimethoxytrityl)-2'-deoxycytidine;N4-BENZOYL-3/'-O-(4,4/'-DIMETHOXYTRITYL)-2/'-DEOXYCYTIDINE

Suppliers and Price of N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N4-Benzoyl-3''-O-(4,4''-dimethoxytrityl)-2''-deoxycytidine
50mg
$ 45.00

Medical Isotopes, Inc.
N4-Benzoyl-3?-O-(4,4?-dimethoxytrityl)-2?-deoxycytidine
1 g
$ 395.00

Biosynth Carbosynth
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
250 mg
$ 300.00

Biosynth Carbosynth
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
100 mg
$ 140.00

Biosynth Carbosynth
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
50 mg
$ 80.00

Biosynth Carbosynth
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
25 mg
$ 50.00

Biosynth Carbosynth
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
500 mg
$ 500.00

American Custom Chemicals Corporation
N4-BENZOYL-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYCYTIDINE 95.00%
5G
$ 1189.65

American Custom Chemicals Corporation
N4-BENZOYL-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYCYTIDINE 95.00%
1G
$ 687.23

Total 12 raw suppliers

Chemical Property of N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Chemical Property:

PSA：121.14000
LogP:5.24290
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:11
Exact Mass:633.24750046
Heavy Atom Count:47
Complexity:1080

Purity/Quality:

97% ^*data from raw suppliers

N4-Benzoyl-3''-O-(4,4''-dimethoxytrityl)-2''-deoxycytidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC4CC(OC4CO)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6
Isomeric SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)O[C@H]4C[C@@H](O[C@@H]4CO)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6

Technology Process of N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

There total 10 articles about N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: N⁴-benzoyl-3'-O-dimethoxytrityl-5'-O-levulinyl-2'-deoxycytidine

: 140712-80-7
N⁴-benzoyl-3'-O-dimethoxytrityl-2'-deoxycytidine

Guidance literature:: With pyridine; acetic acid; hydrazine; In water; at 20 ℃; for 2h; chemoselective reaction;
DOI:10.1021/op050253i

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 4836-13-9
N₄-benzoyl-2'-deoxycytidine

: 67219-55-0
4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine

: 107744-25-2
N⁴-benzoyl-O^3'_,O5'-bis-(4,4'-dimethoxy-trityl)-2'-deoxy-cytidine

: 140712-80-7
N⁴-benzoyl-3'-O-dimethoxytrityl-2'-deoxycytidine

Guidance literature:: 4,4'-dimethoxytrityl chloride; N₄-benzoyl-2'-deoxycytidine; In pyridine; at 20 ℃; for 6h;

With sodium hydrogencarbonate; In water; ethyl acetate; for 2h;

Reference yield:

: 4836-13-9
N₄-benzoyl-2'-deoxycytidine

: 140712-80-7
N⁴-benzoyl-3'-O-dimethoxytrityl-2'-deoxycytidine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / CH₂Cl₂

3: tetrabutylammonium fluoride / tetrahydrofuran

With pyridine; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1081/NCN-200033912