(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Base Information

Chemical Name:(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone
CAS No.:156721-22-1
Molecular Formula:C₃₀H₂₉BrN₂O₅S
Molecular Weight:609.541
Hs Code.:

Synonyms:(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Suppliers and Price of (3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

There total 6 articles about (3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 773-64-8
2-mesitylenesulphonyl chloride

: 156721-22-1
(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / 1.6M butyllithium / tetrahydrofuran; hexane / 1.) -78 deg C - 0 deg C, 55 min, 2.) 0 deg C, 1 h, then RT, 2 h

2: triethylamine / tetrahydrofuran / -78 deg C - 0 deg C, 1 h

3: 1.6M nBuLi in hexane / tetrahydrofuran / -78 - 21 °C

4: 1.) CuBr-Me₂S, methyl sulfide, 2.) N-bromosuccinimide / 1.) THF, ether, 0 deg C, 2 h, then RT, 0.5 h, 2.) THF, -78 deg C, 2, h, then 0 deg C, 0.5 h

With N-Bromosuccinimide; n-butyllithium; dimethylsulfide; triethylamine; In tetrahydrofuran; hexane;
DOI:10.1016/S0040-4020(01)86957-X

Reference yield:

: 156721-17-4
(2-mesitylenesulfonyl)indole-3-acrylic acid

: 156721-22-1
(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / -78 deg C - 0 deg C, 1 h

2: 1.6M nBuLi in hexane / tetrahydrofuran / -78 - 21 °C

3: 1.) CuBr-Me₂S, methyl sulfide, 2.) N-bromosuccinimide / 1.) THF, ether, 0 deg C, 2 h, then RT, 0.5 h, 2.) THF, -78 deg C, 2, h, then 0 deg C, 0.5 h

With N-Bromosuccinimide; n-butyllithium; dimethylsulfide; triethylamine; In tetrahydrofuran;
DOI:10.1016/S0040-4020(01)86957-X

Reference yield:

: 1204-06-4,29953-71-7
trans-3-indole-acrylic acid

: 156721-22-1
(3(2R, 3S), 4R)-3-<2-bromo-3-(N-(2-mesitylenesulfonyl)-3-indolyl)-1-oxobutyl>-4-phenyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / 1.6M butyllithium / tetrahydrofuran; hexane / 1.) -78 deg C - 0 deg C, 55 min, 2.) 0 deg C, 1 h, then RT, 2 h

2: triethylamine / tetrahydrofuran / -78 deg C - 0 deg C, 1 h

3: 1.6M nBuLi in hexane / tetrahydrofuran / -78 - 21 °C

4: 1.) CuBr-Me₂S, methyl sulfide, 2.) N-bromosuccinimide / 1.) THF, ether, 0 deg C, 2 h, then RT, 0.5 h, 2.) THF, -78 deg C, 2, h, then 0 deg C, 0.5 h

With N-Bromosuccinimide; n-butyllithium; dimethylsulfide; triethylamine; In tetrahydrofuran; hexane;
DOI:10.1016/S0040-4020(01)86957-X