(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

Base Information

Chemical Name:(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine
CAS No.:950504-24-2
Molecular Formula:C₂₁H₂₈N₂O₂
Molecular Weight:340.466
Hs Code.:

Synonyms:(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

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Chemical Property of (2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

Chemical Property:

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Technology Process of (2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

There total 1 articles about (2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₁H₂₆N₂O₂

: 950504-24-2
(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃; for 1h;

Reference yield:

: 950504-24-2
(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

: 24424-99-5
di-tert-butyl dicarbonate

: 950504-26-4
(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-carbamic acid tert-butyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 4h;

Reference yield:

: 950504-24-2
(2-pyridin-2-yl-ethyl)-{3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-benzyl}-amine

: 950502-13-3
[3-(2-hydroxy-ethyl)-benzyl]-(2-pyridin-2-yl-ethyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h

2: water; acetic acid / tetrahydrofuran / 10 h / Heating / reflux

With water; acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;