4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

Base Information

Chemical Name:4-(α-hydroxybenzyl)phenoxyacetic ethyl ester
CAS No.:283165-06-0
Molecular Formula:C₁₇H₁₈O₄
Molecular Weight:286.328
Hs Code.:

Synonyms:4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

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Chemical Property of 4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

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Technology Process of 4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

There total 1 articles about 4-(α-hydroxybenzyl)phenoxyacetic ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 833-39-6
4-hydroxy-benzhydrol

: 623-48-3
ethyl iodoacetae

: 283165-06-0
4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide;
DOI:10.1016/S0040-4039(00)00266-5

Reference yield: 100.0%

: 283165-06-0
4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

: 117175-03-8
4-(α-hydroxybenzyl)phenoxyacetic acid

Guidance literature:: With sodium hydroxide; In methanol; water;
DOI:10.1016/S0040-4039(00)00266-5

Reference yield:

: 283165-06-0
4-(α-hydroxybenzyl)phenoxyacetic ethyl ester

: <4-<α-(N-t-Boc-Leu-S)benzyl>phenoxy>acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / NaOH / methanol; H₂O

2: 67 percent / ZnI₂ / CH₂Cl₂ / 17 h / reflux

With sodium hydroxide; zinc(II) iodide; In methanol; dichloromethane; water; 1: Hydrolysis / 2: Acylation;
DOI:10.1016/S0040-4039(00)00266-5