C₁₄H₁₁ClN₄O

Base Information

• Chemical Name: C₁₄H₁₁ClN₄O
• CAS No.: 1352548-02-7
• Molecular Formula: C₁₄H₁₁ClN₄O
• Molecular Weight: 286.721
• Mol file: 1352548-02-7.mol

Synonyms:C₁₄H₁₁ClN₄O

Chemical Property of C₁₄H₁₁ClN₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₁ClN₄O

There total 3 articles about C₁₄H₁₁ClN₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-(1H-tetrazol-5-yl)pyridine (3250-74-6,208264-85-1) + 2-amino-5-chloro-3-methylbenzoyl chloride → C14H11ClN4O (1352548-02-7)

Guidance literature:

With pyridine; In 1,4-dioxane; at 100 ℃;

DOI:10.1021/jf4012467

Reference yield:

pyridine-3-carbonitrile (100-54-9,121697-66-3,1232169-17-3,68271-95-4) → C14H11ClN4O (1352548-02-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 120 - 130 °C

2: pyridine / 1,4-dioxane / 100 °C

With pyridine; sodium azide; ammonium chloride; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1021/jf4012467

Reference yield:

2-amino-5-chloro-3-methylbenzoic acid (20776-67-4) → C14H11ClN4O (1352548-02-7)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / 3 h / Reflux

2: pyridine / 1,4-dioxane / 100 °C

With pyridine; thionyl chloride; In 1,4-dioxane;

DOI:10.1021/jf4012467

upstream raw materials:

pyridine-3-carbonitrile

3-(1H-tetrazol-5-yl)pyridine

2-amino-5-chloro-3-methylbenzoic acid

Downstream raw materials:

C₂₄H₁₅Cl₃N₈O₂S

C₂₄H₁₅BrCl₂N₈O₃

Refernces