diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...

Base Information

• Chemical Name: diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...
• CAS No.: 183479-80-3
• Molecular Formula: C₁₃₁H₂₀₅N₂O₂₄P
• Molecular Weight: 2223.04

Synonyms:diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...

Chemical Property of diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...

There total 2 articles about diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

(2S,3R,4R,5S,6R)-5-Hydroxy-6-hydroxymethyl-3-tetradecanoylamino-4-((R)-3-tetradecanoyloxy-tetradecanoyloxy)-tetrahydro-pyran-2-carboxylic acid benzhydryl ester (179530-63-3) + (2S,3R,4R,5S,6R)-6-Benzyloxycarbonyloxymethyl-5-(diphenoxy-phosphoryloxy)-3-tetradecanoylamino-4-((R)-3-tetradecanoyloxy-tetradecanoyloxy)-tetrahydro-pyran-2-carboxylic acid (183479-79-0) → diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano... (183479-80-3) + (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R,6S)-2-benzyloxycarbonyloxymethyl-6-(1,3-dicyclohexyl-ureidocarbonyl)-3-(diphenoxy-phosphoryloxy)-5-tetradecanoylamino-tetrahydro-pyran-4-yl ester

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 24 ℃; for 16h;

DOI:10.1016/S0040-4020(97)10063-1

Reference yield: 11.0%

1,3-Dicyclohexylurea (2387-23-7) + (2S,3R,4R,5S,6R)-6-Benzyloxycarbonyloxymethyl-5-(diphenoxy-phosphoryloxy)-3-tetradecanoylamino-4-((R)-3-tetradecanoyloxy-tetradecanoyloxy)-tetrahydro-pyran-2-carboxylic acid (183479-79-0) → diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano... (183479-80-3) + (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R,6S)-2-benzyloxycarbonyloxymethyl-6-(1,3-dicyclohexyl-ureidocarbonyl)-3-(diphenoxy-phosphoryloxy)-5-tetradecanoylamino-tetrahydro-pyran-4-yl ester

Guidance literature:

With dmap; diphenylmethyl 2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonate; In dichloromethane; at 24 ℃; for 16h;

DOI:10.1016/S0040-4020(97)10063-1

Reference yield:

diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano... (183479-80-3) → 2,6-anhydro-7-O-{2,6-anhydro-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonic acid

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 24 ℃; for 6h; Yield given;

DOI:10.1016/0040-4039(96)01646-2

upstream raw materials:

1,3-Dicyclohexylurea

(2S,3R,4R,5S,6R)-6-Benzyloxycarbonyloxymethyl-5-(diphenoxy-phosphoryloxy)-3-tetradecanoylamino-4-((R)-3-tetradecanoyloxy-tetradecanoyloxy)-tetrahydro-pyran-2-carboxylic acid

(2S,3R,4R,5S,6R)-5-Hydroxy-6-hydroxymethyl-3-tetradecanoylamino-4-((R)-3-tetradecanoyloxy-tetradecanoyloxy)-tetrahydro-pyran-2-carboxylic acid benzhydryl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 183479-80-3 diphenylmethyl 2,6-anhydro-7-O-{2,6-anhydro-7-O-benzyloxycarbonyl-3-deoxy-5-O-diphenylphosphono-3-tetradecanamido-4-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glycero-D-ido-heptonyl}-3-deoxy-3-tetradecanamino-4-O-[(R)-3-(tetradecanoyloxy)tetradecano...

Send

Send

Metric Ton KG G Pound L ML

Send

Send