benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Base Information

• Chemical Name: benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate
• CAS No.: 1418307-24-0
• Molecular Formula: C₁₉H₁₉ClN₄O₂
• Molecular Weight: 370.838

Synonyms:benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Chemical Property of benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

There total 4 articles about benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

benzyl (2S)-2-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate (1418307-23-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate (1418307-24-0)

Guidance literature:

With trichlorophosphate; In ethyl acetate; at 0 - 20 ℃; for 2h;

Reference yield: 59.0%

benzyl (2S)-2-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate (1418307-23-9) → benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate (1418307-24-0)

Guidance literature:

With 2-fluoropyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 35 ℃;

Reference yield:

benzyl (3R)-3-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate (1419221-77-4) → benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate (1418307-24-0)

Guidance literature:

With 1,3-dimethyl-2-imidazolidinone; trichlorophosphate; In acetonitrile; at 0 - 60 ℃; for 12h;

upstream raw materials:

benzyl (2S)-2-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate

N,N-dimethyl-formamide

benzyl (3R)-3-([(3-chloropyrazin-2-yl)methyl]carbamoyl)piperidine-1-carboxylate

(S)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid

Downstream raw materials:

(S)-benzyl 2-(8-methylimidazo[1 ,5-a]pyrazin-3-yl)piperidine-1-carboxylate

benzyl-(2S)-2-(8-amino-1-bromo-imidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

(S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1418307-24-0 benzyl (2S) -2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send