4-Cyclohexylbutan-1-amine

Base Information

• Chemical Name: 4-Cyclohexylbutan-1-amine
• CAS No.: 4441-59-2
• Molecular Formula: C10H21N
• Molecular Weight: 155.283
• Hs Code.: 2921300090
• European Community (EC) Number: 809-430-0
• DSSTox Substance ID: DTXSID30388904
• Wikidata: Q72459880
• Mol file: 4441-59-2.mol

Synonyms:4-cyclohexylbutan-1-amine;4-CYCLOHEXYL-BUTYLAMINE;4441-59-2;CYCLOHEXANEBUTANAMINE;4-(cyclohexyl)butylamine;SCHEMBL133414;DTXSID30388904;NQJLVGQKPMVHTD-UHFFFAOYSA-N;4-Cyclohexyl-butylamine, AldrichCPR;MFCD00019401;3-(1-cyclohexyl-methyl)-propyl amine;AKOS013465771;AB01262;CS-0341063;FT-0710046;EN300-1849920;A826572

Chemical Property of 4-Cyclohexylbutan-1-amine

Chemical Property:

• Vapor Pressure: 0.17mmHg at 25°C
• Refractive Index: 1.463
• Boiling Point: 212.7 °C at 760 mmHg
• Flash Point: 77.6 °C
• PSA: 26.02000
• Density: 0.859 g/cm³
• LogP: 3.39600
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 155.167399674
• Heavy Atom Count: 11
• Complexity: 84.9

Purity/Quality:

98%Min ^*data from raw suppliers

4-Cyclohexylbutan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)CCCCN

Technology Process of 4-Cyclohexylbutan-1-amine

There total 4 articles about 4-Cyclohexylbutan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-phenyl-1-butylamine (13214-66-9) → 4-cyclohexyl-butylamine (4441-59-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid; at 25 ℃; for 4h; under 2792.6 Torr;

DOI:10.1021/jm00062a013

Reference yield:

3-cyclohexylpropionitrile (4441-66-1) → 4-cyclohexyl-butylamine (4441-59-2)

Guidance literature:

With ammonia; nickel; Hydrogenation;

DOI:10.1021/ja01568a048

Reference yield:

4-cyclohexyl-butyric acid amide (4441-62-7) → 4-cyclohexyl-butylamine (4441-59-2)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01593a049

upstream raw materials:

3-cyclohexylpropionitrile

4-cyclohexyl-butyric acid amide

4-phenyl-1-butylamine

Downstream raw materials:

(4-cyclohexyl-butyl)-[5-(2-diethylamino-ethylidene)-4,5-dihydro-thiazol-2-yl]-amine

4-(4-Cyclohexyl-butylamino)-[1,2]naphthoquinone

N-(4-Cyclohexyl-butyl)-4-(pyridine-3-carbonyl)-benzamide

2-(4-chlorophenoxy)-N-([(4-cyclohexylbutyl)carbamothioyl]amino)-N-methylacetamide

Refernces

• 1、 Misra, Raj N.,Brown, Baerbel R.,Sher, Philip M.,Patel, Manorama M.,Hall, Steven E.,et al.. "Interphenylene 7-Oxabicycloheptane Oxazoles. Highly Potent, Selective, and Long-Acting Thromboxane A2 Receptor Antagonists". . p. 1401 - 1417. Retrieved 2007/10/02.