2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT

Base Information

• Chemical Name: 2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT
• CAS No.: 76204-02-9
• Molecular Formula: C21H25 N O11 . Na
• Molecular Weight: 489.41
• Hs Code.: 29322090
• Mol file: 76204-02-9.mol

Synonyms:D-glycero-a-D-galacto-2-Nonulopyranosidonicacid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl 5-(acetylamino)-3,5-dideoxy-,monosodium salt

Chemical Property of 2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT

Chemical Property:

• Melting Point: 171°C dec.
• PSA: 198.82000
• LogP: -2.31410
• Storage Temp.: −20°C
• Solubility.: H2O: 50 mg/mL, clear, very slightly yellow

Purity/Quality:

98%, ^*data from raw suppliers

4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid sodium salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Description: 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.
• Uses: Used as a substrate in a fluorometric assay of neuraminidase. (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt has been used for fluorometric assay of neuraminidase as well as fluorescent staining of sialidases in PAGE.