diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

Base Information

Chemical Name:diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate
CAS No.:1322668-06-3
Molecular Formula:C₁₉H₂₃FNO₃P
Molecular Weight:363.369
Hs Code.:

Synonyms:diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

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Technology Process of diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

There total 1 articles about diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 78317-79-0
2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline

: 762-04-9
phosphonic acid diethyl ester

: 1322668-06-3
diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

Guidance literature:: With zinc(II) oxide; In ethanol; for 40h; Irradiation;
DOI:10.1002/chem.201103242

Reference yield: 66.0%

: 1322668-06-3
diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

: 2-(4-fluorophenyl)-3,4-dihydroisoquinolin-1(2H)-one

: 2-(4-fluorophenyl)-1(2H)-isoquinolinone

Guidance literature:: With tert.-butylnitrite; N-hydroxyphthalimide; oxygen; In 1,4-dioxane; at 80 ℃; Overall yield = 90 mg;
DOI:10.1039/d1cc00550b

Reference yield: 52.0%

: 1322668-06-3
diethyl 2-(4-fliorophenyl)-1,2,3,4-tetrahydroisoquinoline-1-yl-phosphonate

: 4-bromo-2-(4-fluorophenyl)isoquinolin-1(2H)-one

Guidance literature:: With tert.-butylnitrite; N-hydroxyphthalimide; oxygen; copper(I) bromide; In 1,4-dioxane; at 80 ℃;
DOI:10.1039/d1cc00550b