trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Base Information

Chemical Name:trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone
CAS No.:113999-16-9
Molecular Formula:C₁₉H₂₆O₄S
Molecular Weight:350.479
Hs Code.:

Synonyms:trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Suppliers and Price of trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

There total 3 articles about trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 113999-14-7
3-methyl-3-<<3,3-bis(tosyloxy)methyl>propyl>cyclohexanone

: 113999-15-8
cis-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

: 113999-16-9
trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Guidance literature:: With sodium tert-pentoxide; In benzene; 1.) RT, 2 h, 2.) 50 deg C, 3 h;
DOI:10.1021/jo00246a029

Reference yield:

: 113999-11-4
3-methyl-3-<3,3-bis(hydroxymethyl)propyl>cyclohexanone

: 113999-16-9
trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine / CH₂Cl₂ / 18 h / -20 °C

2: 46 percent / sodium tert-pentoxide / benzene / 1.) RT, 2 h, 2.) 50 deg C, 3 h

With sodium tert-pentoxide; triethylamine; In dichloromethane; benzene;
DOI:10.1021/jo00246a029

Reference yield:

: 113999-10-3
3-<2-(2,2-dimethyl-1,3-dioxan-5-yl)ethyl>-3-methylcyclohexanone

: 113999-16-9
trans-2,3,4,5,6,7,8,9-octahydro-7β-<(tosyloxy)methyl>-10β-methyl-1(10H)-naphthalenone

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / HCl / tetrahydrofuran / 4.5 h / Ambient temperature

2: 80 percent / triethylamine / CH₂Cl₂ / 18 h / -20 °C

3: 46 percent / sodium tert-pentoxide / benzene / 1.) RT, 2 h, 2.) 50 deg C, 3 h

With hydrogenchloride; sodium tert-pentoxide; triethylamine; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1021/jo00246a029