Technology Process of C35H44O6S
There total 12 articles about C35H44O6S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C14H21O5PS;
With
n-butyllithium;
In
hexanes;
at -78 ℃;
for 1h;
C25H34O5;
In
tetrahydrofuran; hexanes;
at -78 - 20 ℃;
for 3h;
optical yield given as %de;
diastereoselective reaction;
DOI:10.1021/jo200934w
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: sodium tetrahydroborate / methanol / 0.33 h / 0 - 25 °C
2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0.67 h / 25 °C
3.1: toluene / 17 h / Reflux
4.1: n-butyllithium / tetrahydrofuran; cyclohexane / 1 h / -78 °C
4.2: 3 h / -78 - 25 °C
5.1: ammonium fluoride / methanol / 15 h / 60 °C
6.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.5 h / -60 °C
6.2: 1.5 h / -78 - 0 °C
7.1: n-butyllithium / hexanes / 1 h / -78 °C
7.2: 3 h / -78 - 20 °C
With
ammonium fluoride; sodium tetrahydroborate; n-butyllithium; oxalyl dichloride; carbon tetrabromide; dimethyl sulfoxide; triphenylphosphine;
In
tetrahydrofuran; methanol; hexanes; dichloromethane; cyclohexane; toluene;
2.1: Appel reaction / 4.2: Horner-Wadsworth-Emmons olefination / 6.1: Swern oxidation / 6.2: Swern oxidation / 7.2: Horner-Wadsworth-Emmons olefination;
DOI:10.1021/jo200934w
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0.67 h / 25 °C
2.1: toluene / 17 h / Reflux
3.1: n-butyllithium / tetrahydrofuran; cyclohexane / 1 h / -78 °C
3.2: 3 h / -78 - 25 °C
4.1: ammonium fluoride / methanol / 15 h / 60 °C
5.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1.5 h / -60 °C
5.2: 1.5 h / -78 - 0 °C
6.1: n-butyllithium / hexanes / 1 h / -78 °C
6.2: 3 h / -78 - 20 °C
With
ammonium fluoride; n-butyllithium; oxalyl dichloride; carbon tetrabromide; dimethyl sulfoxide; triphenylphosphine;
In
tetrahydrofuran; methanol; hexanes; dichloromethane; cyclohexane; toluene;
1.1: Appel reaction / 3.2: Horner-Wadsworth-Emmons olefination / 5.1: Swern oxidation / 5.2: Swern oxidation / 6.2: Horner-Wadsworth-Emmons olefination;
DOI:10.1021/jo200934w
