Technology Process of C27H27NO4
There total 5 articles about C27H27NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,2-diphenylacetic acid;
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 20 ℃;
for 5h;
4(R)-(phenylmethoxy)-(S)-proline methyl ester;
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: thionyl chloride / 7 h / Reflux
2.1: triethylamine / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
3.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 5 h / 20 - 35 °C
4.2: pH 8
5.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 5 h / 0 - 20 °C
5.2: 0 - 20 °C
With
thionyl chloride; oxalyl dichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; N,N-dimethyl-formamide; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; mineral oil;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran; mineral oil / 0 - 20 °C
2.1: trifluoroacetic acid / dichloromethane / 5 h / 20 - 35 °C
2.2: pH 8
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 5 h / 0 - 20 °C
3.2: 0 - 20 °C
With
oxalyl dichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; N,N-dimethyl-formamide; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane; mineral oil;
