(R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene

Base Information

• Chemical Name: (R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene
• CAS No.: 1229984-76-2
• Molecular Formula: C₁₉H₂₂O₂
• Molecular Weight: 282.382
• Mol file: 1229984-76-2.mol

Synonyms:(R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene

Chemical Property of (R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene

There total 1 articles about (R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

(R)-2-phenyl-pent-4-en-2-ol (4743-74-2,100350-03-6,110577-97-4) + p-methoxybenzyl chloride (824-94-2) → (R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene (1229984-76-2)

Guidance literature:

(R)-2-phenyl-pent-4-en-2-ol; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

p-methoxybenzyl chloride; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.tet.2010.03.048

Reference yield:

(R)-1-methoxy-4-((2-phenylpent-4-en-2-yloxy)methyl)-benzene (1229984-76-2) → (2S,4R)-4-(4-methoxybenzyloxy)-4-phenylpentane-1,2-diol (1229985-01-6) + (2R,4R)-4-(4-methoxybenzyloxy)-4-phenylpentane-1,2-diol (1229984-98-8)

Guidance literature:

With potassium osmate; 4-methylmorpholine N-oxide; In water; acetone; at 0 - 20 ℃; for 12h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2010.03.048

upstream raw materials:

(R)-2-phenyl-pent-4-en-2-ol

p-methoxybenzyl chloride

Downstream raw materials:

(2S,4R)-4-(4-methoxybenzyloxy)-4-phenylpentane-1,2-diol

(2R,4R)-4-(4-methoxybenzyloxy)-4-phenylpentane-1,2-diol