4-Bromo-5-fluorobenzene-1,2-diamine

Base Information

Chemical Name:4-Bromo-5-fluorobenzene-1,2-diamine
CAS No.:153505-37-4
Molecular Formula:C6H6BrFN2
Molecular Weight:205.029
Hs Code.:2921590090
European Community (EC) Number:640-288-0
DSSTox Substance ID:DTXSID70601467
Wikidata:Q82498152
Mol file:153505-37-4.mol

Synonyms:4-Bromo-5-fluorobenzene-1,2-diamine;153505-37-4;1,2-Benzenediamine, 4-bromo-5-fluoro-;4-Bromo-5-fluoro-1,2-phenylenediamine;MFCD08458150;4-bromo-5-fluoro-1,2-benzenediamine;4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98;4-Bromo-5-fluoro-o-phenylenediamine;SCHEMBL241198;DTXSID70601467;NDXWAQNAHFBGML-UHFFFAOYSA-N;4-Bromo-5-fluoro-1,2-diaminobenzene;AKOS013154142;4-bromo-5- fluorobenzene-l,2-diamine;CCG-302588;PS-8114;SB78077;1,2-Benzenediamine,4-bromo-5-fluoro-;SY035383;4-bromanyl-5-fluoranyl-benzene-1,2-diamine;CS-0098663;4-Bromo-5-fluorobenzene-1 pound not2-diamine;EN300-98948;F30213;A809434;Z1269223296;4-Bromo-5-fluorophenylene-1,2-diamine, 1-Bromo-4,5-diamino-2-fluorobenzene

Suppliers and Price of 4-Bromo-5-fluorobenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-5-fluorobenzene-1,2-diamine
100mg
$ 60.00

SynQuest Laboratories
4-Bromo-5-fluoro-1,2-phenylenediamine 98%
25 g
$ 751.00

SynQuest Laboratories
4-Bromo-5-fluoro-1,2-phenylenediamine 98%
1 g
$ 77.00

SynQuest Laboratories
4-Bromo-5-fluoro-1,2-phenylenediamine 98%
5 g
$ 232.00

Matrix Scientific
4-Bromo-5-fluorobenzene-1,2-diamine 95+%
5g
$ 605.00

Matrix Scientific
4-Bromo-5-fluorobenzene-1,2-diamine 95+%
1g
$ 227.00

Matrix Scientific
4-Bromo-5-fluorobenzene-1,2-diamine 95+%
10g
$ 914.00

Crysdot
4-Bromo-5-fluorobenzene-1,2-diamine 98%
10g
$ 327.00

Chemenu
4-Bromo-5-fluorobenzene-1,2-diamine 95+%
10g
$ 318.00

Chemenu
4-Bromo-5-fluorobenzene-1,2-diamine 95+%
25g
$ 636.00

Total 29 raw suppliers

Chemical Property of 4-Bromo-5-fluorobenzene-1,2-diamine

Chemical Property:

Vapor Pressure:0.00139mmHg at 25°C
Refractive Index:1.663
Boiling Point:297 °C at 760 mmHg
PKA:3.15±0.10(Predicted)
Flash Point:133.4 °C
PSA：52.04000
Density:1.792 g/cm³
LogP:2.91500
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:203.96984
Heavy Atom Count:10
Complexity:122

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-5-fluorobenzene-1,2-diamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1F)Br)N)N

Technology Process of 4-Bromo-5-fluorobenzene-1,2-diamine

There total 5 articles about 4-Bromo-5-fluorobenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 153505-36-3
4-bromo-5-fluoro-2-nitroaniline

: 153505-37-4
4-bromo-5-fluoro-1,2-benzenediamine

Guidance literature:: With ammonium formate; zinc; In methanol; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

: 153505-36-3
4-bromo-5-fluoro-2-nitroaniline

: SnCl2 °2H2 O

: 153505-37-4
4-bromo-5-fluoro-1,2-benzenediamine

Guidance literature:: With sodium hydrogencarbonate; In ethanol; ethyl acetate;

Reference yield:

: 2369-11-1
5-fluoro-2-nitroaniline

: 153505-37-4
4-bromo-5-fluoro-1,2-benzenediamine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; N-Bromosuccinimide / 1.5 h / Reflux

2: tin(ll) chloride / ethanol / 14 h / Reflux

With N-Bromosuccinimide; acetic acid; tin(ll) chloride; In ethanol;