1,3,5-Tris(bromomethyl)benzene

Base Information

• Chemical Name: 1,3,5-Tris(bromomethyl)benzene
• CAS No.: 18226-42-1
• Molecular Formula: C9H9Br3
• Molecular Weight: 356.882
• Hs Code.: 29039990
• Mol file: 18226-42-1.mol

Synonyms:1,3,5-Tri(bromomethyl)benzene;2,4,6-Tri(bromomethyl)benzene;a,a',a''-Tribromomesitylene;

Chemical Property of 1,3,5-Tris(bromomethyl)benzene

Chemical Property:

• Appearance/Colour: White to pale yellow solid
• Vapor Pressure: 7.93E-05mmHg at 25°C
• Melting Point: 94-99 °C
• Refractive Index: 1.641
• Boiling Point: 352.2 °C at 760 mmHg
• Flash Point: 162.5 °C
• PSA: 0.00000
• Density: 2.005 g/cm³
• LogP: 4.37130

Purity/Quality:

99% ^*data from raw suppliers

1,3,5-Tris(bromomethyl)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,3,5-Tris(bromomethyl)benzene can be used to treat bacterial infections and potentiation of antibiotics.

Technology Process of 1,3,5-Tris(bromomethyl)benzene

There total 20 articles about 1,3,5-Tris(bromomethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

propargyl bromide (106-96-7) → 1,3,5-Tris(bromomethyl)benzene (18226-42-1)

Guidance literature:

With chloro-trimethyl-silane; In butan-1-ol; benzene; at 80 ℃; for 16h; regioselective reaction; Inert atmosphere;

DOI:10.1166/jnn.2011.4173

Reference yield: 98.0%

1,3,5-tris(hydroxymethyl)benzene (4464-18-0) → 1,3,5-Tris(bromomethyl)benzene (18226-42-1)

Guidance literature:

With hydrogen bromide; In acetic acid; at 20 ℃; for 46h;

DOI:10.1002/anie.199727811

Reference yield: 96.0%

1,3,5-trimethyl-benzene (108-67-8) → 1,3,5-Tris(bromomethyl)benzene (18226-42-1)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; at 70 ℃; for 6h;

DOI:10.1039/c4nj02395a

upstream raw materials:

3,5-bis(bromomethyl)toluene

1,3,5-tris(hydroxymethyl)benzene

1,3,5-trimethyl-benzene

1,3-Bis(hydroxymethyl)-5-(methoxymethyl)benzol

Downstream raw materials:

1,3,5-Tris<(2-methylaziridinyl-1)methyl>benzene

1,3,5-tris(pyrazole-1-yl-methyl)benzene

1,3,5-tris-[3,5-bis(methoxycarbonyl)phenoxymethyl]benzene

5,15,23,33,38,48-Hexatosyl-5,15,23,33,38,48-hexaazadecacyclo<17.15.15.2^6,9.2^11,14.2^24,27.2^29,32.2^39,42.2^44,47.1^3,37.1^17,21>trihexaconta-1,3,6,8,11,13,17,19,21,24,26,29,31,35,39,41,44,46,50,52,55,57,60,62-tetradodecaen

Refernces

• 1、 An, Wen,Aulakh, Darpandeep,Zhang, Xuan,Verdegaal, Wolfgang,Dunbar, Kim R.,Wriedt, Mario. "Switching of Adsorption Properties in a Zwitterionic Metal-Organic Framework Triggered by Photogenerated Radical Triplets". . p. 7825 - 7832. Retrieved 2016.
• 2、 González, Alfonso,Segura, José L.,Martín, Nazario. "New planar and soluble tris-tetrathiafulvalene derivatives with threefold-symmetry". . p. 3083 - 3086. Retrieved 2000.
• 3、 Hermann, Keith,Pratumyot, Yaowalak,Polen, Shane,Hardin, Alex M.,Dalkilic, Erdin,Dastan, Arif,Badji?, Jovica D.. "Twisted baskets". . p. 3550 - 3555. Retrieved 2015.
• 4、 Liu, Guoliang,Wang, Yangxin,Shen, Chaojun,Ju, Zhanfeng,Yuan, Daqiang. "A facile synthesis of microporous organic polymers for efficient gas storage and separation". . p. 3051 - 3058. Retrieved 2015.
• 5、 Yang, Chaolong,Luo, Jianxin,Ma, Jianying,Lu, Mangeng,Liang, Liyan,Tong, Bihai. "Synthesis and photoluminescent properties of four novel trinuclear europium complexes based on two tris-β-diketones ligands". . p. 696 - 704. Retrieved 2012.
• 6、 Helbing, Tim,Carraro, Caterina,Francke, Alexander,Sosic, Alice,De Franco, Michele,Gandin, Valentina,G?ttlich, Richard,Gatto, Barbara. "Aromatic Linkers Unleash the Antiproliferative Potential of 3-Chloropiperidines Against Pancreatic Cancer Cells". supporting information. p. 2040 - 2051. Retrieved 2020/09/21.
• 7、 Shang, Qigao,Zeng, Tianyu,Gao, Ke,Liu, Nannan,Cheng, Qingrong,Liao, Guiying,Pan, Zhiquan,Zhou, Hong. "A novel nitrogen heterocyclic ligand-based MOF: Synthesis, characterization and photocatalytic properties". supporting information. p. 16595 - 16603. Retrieved 2019/11/11.