(S)-(+)-2-phenylvaleric acid

Base Information

• Chemical Name: (S)-(+)-2-phenylvaleric acid
• CAS No.: 7782-25-4
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.231

Synonyms:(S)-(+)-2-phenylvaleric acid

Chemical Property of (S)-(+)-2-phenylvaleric acid

Chemical Property:

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Technology Process of (S)-(+)-2-phenylvaleric acid

There total 15 articles about (S)-(+)-2-phenylvaleric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

2-phenyl-2-propyl acetamide (14387-51-0) → (S)-(+)-2-phenylvaleric acid (7782-25-4,5558-45-2)

Guidance literature:

With potassium phosphate buffer; Rhodococcus sp. AJ₂₇₀; at 30 ℃; for 325h; pH=7.0;

DOI:10.1016/S0957-4166(00)00025-2

Reference yield: 14.0%

2-phenyl-pentanenitrile (5558-78-1) → (S)-(+)-2-phenylvaleric acid (7782-25-4,5558-45-2) + (S)-2-phenylvaleramide (13490-77-2) + (R)-(-)-2-phenylvaleramide (281230-10-2)

Guidance literature:

With Rhodococcus sp. CGMCC 0497; In phosphate buffer; for 50h; pH=7.0;

DOI:10.1016/S0957-4166(02)00017-4

Reference yield: 13.0%

2-phenyl-pentanenitrile (5558-78-1) → (S)-(+)-2-phenylvaleric acid (7782-25-4,5558-45-2)

Guidance literature:

With potassium phosphate buffer; Rhodococcus sp. AJ₂₇₀; at 30 ℃; for 214h; pH=7.0;

DOI:10.1016/S0957-4166(00)00025-2

upstream raw materials:

(S)-2-phenyl-4-pentenoic acid

(RS)-2-phenylpentanoic acid

2-phenyl-pentanenitrile

2-phenyl-2-propyl acetamide

Downstream raw materials:

(S)-3-phenyl-hexan-2-one

(S)-4-phenylheptan-3-one

(S)-2-cyclohexyl-valeric acid

D-2-phenyl-valeronitrile

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