Technology Process of (4-Benzofuran-2-yl-4,5-dihydro-3H-pyrrol-2-yl)-phenyl-amine
There total 12 articles about (4-Benzofuran-2-yl-4,5-dihydro-3H-pyrrol-2-yl)-phenyl-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine
2: 1.) thionyl chloride / 1.) 100 deg C, 30 min; 2.) 70 deg C, 100 deg C, 15 min
3: 70 percent / trimethylbenzyl ammonium hydroxide / 16 h / 70 °C
4: 80 percent / hydrogen / Raney nickel / ethanol / 60 °C
5: 70 percent / CH2Cl2 / 1 h
6: ethanol / 24 h / Heating
With
pyridine; thionyl chloride; hydrogen; N-benzyl-trimethylammonium hydroxide;
nickel;
In
ethanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: potassium carbonate / dimethylformamide
2: acetic acide / Heating
3: pyridine
4: 1.) thionyl chloride / 1.) 100 deg C, 30 min; 2.) 70 deg C, 100 deg C, 15 min
5: 70 percent / trimethylbenzyl ammonium hydroxide / 16 h / 70 °C
6: 80 percent / hydrogen / Raney nickel / ethanol / 60 °C
7: 70 percent / CH2Cl2 / 1 h
8: ethanol / 24 h / Heating
With
pyridine; thionyl chloride; hydrogen; N-benzyl-trimethylammonium hydroxide; potassium carbonate; acetic acid;
nickel;
In
ethanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: acetic acide / Heating
2: pyridine
3: 1.) thionyl chloride / 1.) 100 deg C, 30 min; 2.) 70 deg C, 100 deg C, 15 min
4: 70 percent / trimethylbenzyl ammonium hydroxide / 16 h / 70 °C
5: 80 percent / hydrogen / Raney nickel / ethanol / 60 °C
6: 70 percent / CH2Cl2 / 1 h
7: ethanol / 24 h / Heating
With
pyridine; thionyl chloride; hydrogen; N-benzyl-trimethylammonium hydroxide; acetic acid;
nickel;
In
ethanol; dichloromethane;