BOC-N-METHYL-TRANEXAMIC ACID

Base Information

• Chemical Name: BOC-N-METHYL-TRANEXAMIC ACID
• CAS No.: 165947-29-5
• Molecular Formula: C14H25 N O4
• Molecular Weight: 271.357
• Hs Code.: 29225090
• Mol file: 165947-29-5.mol

Synonyms:BOC-N-METHYL-TRANEXAMIC ACID;TRANS-4-(BOC-METHYLAMINOMETHYL)-CYCLOHEXANE CARBOXYLIC ACID

Chemical Property of BOC-N-METHYL-TRANEXAMIC ACID

Chemical Property:

• Boiling Point: 389.9±11.0 °C(Predicted)
• PKA: 4.86±0.10(Predicted)
• PSA: 66.84000
• Density: 1.087±0.06 g/cm3(Predicted)
• LogP: 2.74430

Purity/Quality:

99% ^*data from raw suppliers

Boc,Me-AMCHC ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-N-METHYL-TRANEXAMIC ACID

There total 1 articles about BOC-N-METHYL-TRANEXAMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

→ trans-4-((tert-butoxycarbonyl(methyl)amino)methyl)cyclohexanecarboxylic acid (165947-29-5)

Guidance literature:

Reference yield: 99.5%

4-(piperidin-4-yl)pyridine (581-45-3) + trans-4-((tert-butoxycarbonyl(methyl)amino)methyl)cyclohexanecarboxylic acid (165947-29-5) → tert-butyl methyl((4-(4-(pyridin-4-yl)piperidine-1-carbonyl)cyclohexyl)methyl)carbamate

Guidance literature:

With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 17h;

Reference yield: 93.8%

trans-4-((tert-butoxycarbonyl(methyl)amino)methyl)cyclohexanecarboxylic acid (165947-29-5) + (R)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole → C26H37N3O3

Guidance literature:

With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 17h;

Refernces