7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one

Base Information

Chemical Name:7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one
CAS No.:862700-70-7
Molecular Formula:C₄₂H₆₁F₅O₅S
Molecular Weight:773.001
Hs Code.:
Mol file:862700-70-7.mol

Synonyms:3,17β-bis(2-tetrahydropyranyloxy)-7α-[9-(4,4,5,5,5-pentafluoropentyl)thiononyl]estra-1,3,5(10)-triene-6-one

Suppliers and Price of 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
S-Deoxo-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)-6-oxo-fulvestrant
5 mg
$ 675.00

Total 2 raw suppliers

Chemical Property of 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one

Chemical Property:

Solubility.:Dichloromethane, Diethyl Ether, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

S-Deoxo-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)-6-oxo-fulvestrant ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Fulvestrant (F862500) impurity E derivative. Used in the preparation of antiestrogenic 17-alkylene-16α-hydroxyestratrienes for cancer treatment. S-Deoxo-3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)-6-oxo-fulvestrant is Fulvestrant (F862500) impurity E derivative. Used in the preparation of antiestrogenic 17-alkylene-16α-hydroxyestratrienes for cancer treatment.

Technology Process of 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one

There total 10 articles about 7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl]--3,17β-bis-(O-tetrahydro-2H-pyran-2-yl)estra-1,3,5(10)-triene-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 862700-70-7
3,17β-bis(2-tetrahydropyranyloxy)-7α-[9-(4,4,5,5,5-pentafluoropentyl)thiononyl]estra-1,3,5(10)-triene-6-one

Guidance literature:

Reference yield: 43.1%

: 862700-63-8
1-iodo-9-(4,4,5,5,5-pentafluoro-pentylsulfanyl)-nonane

: 53573-82-3
3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene-6-one

: 862700-70-7
3,17β-bis(2-tetrahydropyranyloxy)-7α-[9-(4,4,5,5,5-pentafluoropentyl)thiononyl]estra-1,3,5(10)-triene-6-one

Guidance literature:: 3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene-6-one; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 1.25h;

1-iodo-9-(4,4,5,5,5-pentafluoro-pentylsulfanyl)-nonane; In tetrahydrofuran; at -70 ℃; for 15h;