4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

Base Information

Chemical Name:4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester
CAS No.:1078132-88-3
Molecular Formula:C₁₃H₇F₃O₃
Molecular Weight:268.192
Hs Code.:

Synonyms:4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

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Chemical Property of 4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

Chemical Property:

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Technology Process of 4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

There total 2 articles about 4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1201-31-6
2,3,4,5-tetrafluorobenzoic acid

: 106-96-7
propargyl bromide

: 1078132-88-3
4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

Guidance literature:: 2,3,4,5-tetrafluorobenzoic acid; With water; sodium hydroxide; for 4h; Reflux;

With hydrogenchloride; In water;

propargyl bromide; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield:

: 106-96-7
propargyl bromide

: 156839-10-0
2,3,5-trifluoro-4-hydroxybenzoic acid

: 1078132-88-3
4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield:

: 1078132-88-3
4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester

: 1078132-89-4
4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid

Guidance literature:: 4-(2-propynyloxy)-2,3,5-trifluorobenzoic acid 2-propynyl ester; With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 20 - 50 ℃; for 4h;

With hydrogenchloride; In tetrahydrofuran; water;