C₂₅H₂₁ClF₃N₅O₂

Base Information

Chemical Name:C₂₅H₂₁ClF₃N₅O₂
CAS No.:1258641-52-9
Molecular Formula:C₂₅H₂₁ClF₃N₅O₂
Molecular Weight:515.922
Hs Code.:

C<sub>25</sub>H<sub>21</sub>ClF<sub>3</sub>N<sub>5</sub>O<sub>2</sub>

Synonyms:C₂₅H₂₁ClF₃N₅O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₅H₂₁ClF₃N₅O₂

Chemical Property:

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Technology Process of C₂₅H₂₁ClF₃N₅O₂

There total 6 articles about C₂₅H₂₁ClF₃N₅O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1258641-59-6
C₃₃H₂₅ClF₃N₅O₅

: 1258641-52-9
C₂₅H₂₁ClF₃N₅O₂

Guidance literature:: C₃₃H₂₅ClF₃N₅O₅; With hydrazine hydrate; In methanol; dichloromethane; for 1h;

With phosphorus pentoxide; In ethanol; Reflux;

Reference yield:

: 1258641-56-3
C₁₅H₂₃F₃O₂Si

: 1258641-52-9
C₂₅H₂₁ClF₃N₅O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 48.5 h / 0 - 80 °C

2.1: potassium carbonate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 48 h / Heating

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h

4.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 2.5 h / 0 - 80 °C

5.1: hydrazine hydrate / dichloromethane; methanol / 1 h

5.2: Reflux

With hydrazine hydrate; tributylphosphine; tetrabutyl ammonium fluoride; potassium carbonate; 1,1'-azodicarbonyl-dipiperidine; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; methanol; dichloromethane; toluene; 4.1: Mitsunobu reaction;

Reference yield:

: 1258641-57-4
C₂₀H₂₄BrClF₃NO₂Si

: 1258641-52-9
C₂₅H₂₁ClF₃N₅O₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 48 h / Heating

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h

3.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 2.5 h / 0 - 80 °C

4.1: hydrazine hydrate / dichloromethane; methanol / 1 h

4.2: Reflux

With hydrazine hydrate; tributylphosphine; tetrabutyl ammonium fluoride; potassium carbonate; 1,1'-azodicarbonyl-dipiperidine; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; methanol; dichloromethane; toluene; 3.1: Mitsunobu reaction;