(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

Base Information

Chemical Name:(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride
CAS No.:1309250-94-9
Molecular Formula:C₂₈H₅₃N₃O₆*ClH
Molecular Weight:564.206
Hs Code.:

Synonyms:(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

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Chemical Property of (3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

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Technology Process of (3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

There total 7 articles about (3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1309250-93-8
C₃₃H₆₁N₃O₈

: 1309250-94-9
(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 0.5h;

Reference yield:

: 4-amino-5-cyclohexyl-3-hydroxy-pentanoic acid ethyl ester

: 1309250-94-9
(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: benzotriazol-1-ol; dicyclohexyl-carbodiimide

2: water / Alkaline conditions

3: benzotriazol-1-ol; dicyclohexyl-carbodiimide

4: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C

With hydrogenchloride; water; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In 1,4-dioxane;

Reference yield:

: 53363-89-6
N-t-butoxycarbonyl-N-methyl-L-leucine

: 1309250-94-9
(3S,4S)-4-((3S,4S)-4-(N-methylleucylamino)-5-cyclohexyl-3-hydroxypentanoylamino)-3-hydroxy-6-methylheptanoic acid ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: benzotriazol-1-ol; dicyclohexyl-carbodiimide

2: water / Alkaline conditions

3: benzotriazol-1-ol; dicyclohexyl-carbodiimide

4: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C

With hydrogenchloride; water; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In 1,4-dioxane;