(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

Base Information

Chemical Name:(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione
CAS No.:1280555-50-1
Molecular Formula:C₃₀H₃₁FN₆O₆S
Molecular Weight:622.677
Hs Code.:

Synonyms:(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

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Chemical Property of (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

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Technology Process of (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

There total 1 articles about (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 107089-76-9
NSC 373853

: 198410-25-2
(S)-N-(3-(3-fluoro-4-((N-4-carbobenzoxy)piperazin-1-yl)phenyl)-2-oxo-oxazolidin-5-yl)methylamine

: 1280555-50-1
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2010.12.028

Reference yield: 90.0%

: 1280555-50-1
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

: 1280555-54-5
C₂₂H₂₅FN₆O₄S

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2010.12.028

Reference yield:

: 1280555-50-1
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-methyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

: 1280555-61-4
C₃₅H₃₂ClFN₆O₆S

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 20 °C

With palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2010.12.028