3-Hydroxy-5-androsten-17-one

Base Information

Chemical Name:3-Hydroxy-5-androsten-17-one
CAS No.:25375-38-6
Molecular Formula:C₁₉H₂₈O₂
Molecular Weight:288.43
Hs Code.:
DSSTox Substance ID:DTXSID40858986
Nikkaji Number:J671.849C

Synonyms:3-Hydroxy-5-androsten-17-one;SCHEMBL1126821;DTXSID40858986;BCP05749;AKOS015894876;AKOS015995299;25375-38-6

Suppliers and Price of 3-Hydroxy-5-androsten-17-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Hydroxy-5-androsten-17-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:288.208930132
Heavy Atom Count:21
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CCC(C4)O)C

Technology Process of 3-Hydroxy-5-androsten-17-one

There total 16 articles about 3-Hydroxy-5-androsten-17-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 853-23-6,5223-99-4,18462-31-2,33203-18-8,33855-01-5,104597-49-1
3β-acetoxy-5-androsten-17-one

: 53-43-0,571-35-7,2283-82-1,24357-33-3,25375-38-6,102340-20-5
dehydroepiandrosterone

Guidance literature:: With Aliquat 336; potassium hydroxide; In water; at 60 ℃; for 1.5h;
DOI:10.1039/c2gc16328d

Reference yield: 68.0%

: 14425-92-4,133522-43-7
6β-methoxy-3α,5α-cyclo-14β-androstan-17-one

: 53-43-0,571-35-7,2283-82-1,24357-33-3,25375-38-6,102340-20-5
3β-hydroxy-14β-androst-5-en-17-one

Guidance literature:: With perchloric acid; In acetone; for 2h; Ambient temperature;

Reference yield: 40.0%

: androsterone

: 571-44-8,2791-99-3,86420-28-2
3-alpha-hydroxy-androst-4-en-17-one

: 53-43-0,571-35-7,2283-82-1,24357-33-3,25375-38-6,102340-20-5
3α-hydroxy-androst-5-en-17-one

Guidance literature:: androsterone; With 1-(diphenylphosphino)ferrocene-1-(di-tert-butylphosphino)ferrocene; palladium diacetate; caesium carbonate; In benzene; at 20 ℃; Inert atmosphere; Glovebox; Irradiation;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; benzene; at 20 ℃; Overall yield = 43 %; regioselective reaction; Inert atmosphere; Glovebox;
DOI:10.1021/jacs.7b08459