N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide

Base Information

• Chemical Name: N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide
• CAS No.: 124415-81-2
• Molecular Formula: C₁₈H₂₄N₂OS
• Molecular Weight: 316.467

Synonyms:N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide

Chemical Property of N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide

There total 2 articles about N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-N-(2-methylphenyl)propanamide (61495-04-3) + 2-methyliminomethyl thiophene (142352-11-2) → N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide (124415-81-2)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; methanol; hexane; water; ethyl acetate; toluene;

Reference yield:

N-[(thiophen-2-yl)methylene]methanamine (54433-71-5) + 2,2-dimethyl-N-(2-methylphenyl)propanamide (61495-04-3) → N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide (124415-81-2)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) hexane, THF, 2-10 deg C, 2.) hexane, THF, 0-10 deg C, 1 h;

DOI:10.1021/jm00045a004

Reference yield:

N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide (124415-81-2) → 2-amino-N-methyl-α-(thien-2-yl)benzeneethanamine (124415-82-3)

Guidance literature:

With hydrogenchloride; at 100 ℃; for 24h;

DOI:10.1021/jm00045a004

upstream raw materials:

N-[(thiophen-2-yl)methylene]methanamine

2,2-dimethyl-N-(2-methylphenyl)propanamide

2-methyliminomethyl thiophene

Downstream raw materials:

2-amino-N-methyl-α-(thien-2-yl)benzeneethanamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 124415-81-2 N-[2-[2-methylamino-2-(thien-2-yl)ethyl]phenyl]-2,2-dimethylpropanamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send