TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE

Base Information

Chemical Name:TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE
CAS No.:132183-16-5
Molecular Formula:C29H33 N3 O5 Si
Molecular Weight:531.684
Hs Code.:
Mol file:132183-16-5.mol

Synonyms:b-D-Galactopyranose,2-azido-2-deoxy-1-O-[(1,1-dimethylethyl)diphenylsilyl]-4,6-O-(phenylmethylene)-,(S)-; Pyrano[3,2-d]-1,3-dioxin, b-D-galactopyranose deriv.

Suppliers and Price of TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-O-TERT-BUTYLDIPHENYSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE 95.00%
5MG
$ 501.56

Total 7 raw suppliers

Chemical Property of TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE

Chemical Property:

PSA：106.90000
LogP:3.89466

Purity/Quality:

98%Min ^*data from raw suppliers

1-O-TERT-BUTYLDIPHENYSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE

There total 7 articles about TERT-BUTYLDIPHENYLSILYL-2-AZIDO-4,6-O-BENZYLIDENE-2-DEOXY-BETA-D-GALACTOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 3-O-acetyl-2-azido-4,6-O-benzylidene-2-deoxy-D-galactose

: 132183-16-5
tert-butyldiphenylsilyl O-2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: tert-butylchlorodiphenylsilane; 3-O-acetyl-2-azido-4,6-O-benzylidene-2-deoxy-D-galactose; With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 8h; Inert atmosphere;

With sodium methylate; In methanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.3762/bjoc.13.19

Reference yield:

: 132183-13-2
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-azido-6-hydroxytetrahydro-2H-pyran-3,4-diyl diacetate

: 132183-16-5
tert-butyldiphenylsilyl O-2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / imidazole / dimethylformamide / 2.5 h / 60 °C

2: NaOMe / methanol

3: p-TsOH / acetonitrile

With 1H-imidazole; sodium methylate; toluene-4-sulfonic acid; In methanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4039(00)97201-0

Reference yield:

: 132183-14-3
(2R,3R,4R,5R,6S)-2-(acetoxymethyl)-5-azido-6-((tert-butyldiphenylsilyl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate

: 132183-16-5
tert-butyldiphenylsilyl O-2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol

2: p-TsOH / acetonitrile

With sodium methylate; toluene-4-sulfonic acid; In methanol; acetonitrile;
DOI:10.1016/S0040-4039(00)97201-0