BENZYL-2,3-ANHYDRO-ALPHA-D-RIBOPYRANOSIDE

Base Information

• Chemical Name: BENZYL-2,3-ANHYDRO-ALPHA-D-RIBOPYRANOSIDE
• CAS No.: 61134-24-5
• Molecular Formula: C12H14 O4
• Molecular Weight: 222.241
• Hs Code.: 2932999099
• Mol file: 61134-24-5.mol

Synonyms:3,7-Dioxabicyclo[4.1.0]heptane,a-D-ribopyranoside deriv.; Benzyl2,3-anhydro-a-D-ribopyranoside

Chemical Property of BENZYL-2,3-ANHYDRO-ALPHA-D-RIBOPYRANOSIDE

Chemical Property:

• PSA: 51.22000
• LogP: 0.68780

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZYL-2,3-ANHYDRO-ALPHA-D-RIBOPYRANOSIDE

There total 12 articles about BENZYL-2,3-ANHYDRO-ALPHA-D-RIBOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

benzyl 2-O-p-tosyl-α-D-arabinopyranoside (61134-28-9) → Benzyl 2,3-anhydro-α-D-ribopyranoside (61134-24-5)

Guidance literature:

With sodium methylate; In methanol;

Reference yield:

Methanesulfonic acid (1R,5R,6S,9S)-6-benzyloxy-3-phenyl-2,4,7-trioxa-3-bora-bicyclo[3.3.1]non-9-yl ester → Benzyl 2,3-anhydro-α-D-ribopyranoside (61134-24-5) + benzyl 3,4-anhydro-α-D-ribopyranoside (112482-94-7)

Guidance literature:

With sodium methylate; In methanol; at 25 ℃; for 1h;

DOI:10.1002/1522-2675(200205)85:5<1443::AID-HLCA1443>3.0.CO;2-U

Reference yield:

benzyl O2,O4-phenylboranediyl-α-D-xylopyranoside (6894-01-5) → Benzyl 2,3-anhydro-α-D-ribopyranoside (61134-24-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / 1 h / 25 °C

2: NaOMe / methanol / 1 h / 25 °C

With sodium methylate; triethylamine; In methanol;

DOI:10.1002/1522-2675(200205)85:5<1443::AID-HLCA1443>3.0.CO;2-U

upstream raw materials:

benzyl 2-O-p-tosyl-α-D-arabinopyranoside

benzyl O²,O⁴-phenylboranediyl-α-D-xylopyranoside

benzyl β-D-xylopyranoside

benzyl 2,3,4-tri-O-benzoyl-α-D-arabinopyranoside

Downstream raw materials:

(-)-(2S)-benzyloxy-2,5-dihydrofuran-4-carboxaldehyde

benzyl 3-chloro-3-deoxy-α-D-xylopyranoside

3-methoxy-3-deoxy-2,4-di-O-benzoyl-α-D-xylopyranoside

benzyl 3-(phenylthio)-3-deoxy-2,4-di-O-benzoyl-α-D-xylopyranoside