N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine

Base Information

• Chemical Name: N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine
• CAS No.: 220261-03-0
• Molecular Formula: C₃₅H₅₆N₄O₂S₂
• Molecular Weight: 628.987
• Mol file: 220261-03-0.mol

Synonyms:N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine

Chemical Property of N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine

There total 4 articles about N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzylidene>propane-1,3-diamine → N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine (220261-03-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; dichloromethane; for 2h;

DOI:10.1002/(SICI)1099-0682(199901)1999:1<179::AID-EJIC179>3.0.CO;2-5

Reference yield:

2-bromo-5-tert-butyl-1,3-benzenedicarbaldehyde (212752-04-0) → N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine (220261-03-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 95 percent / K₂CO₃ / dimethylformamide / 12 h

2: 69 percent / H₂N-OH*HCl, NEt₃ / CHCl₃ / 12 h

3: 93 percent / ethanol / 0.17 h / 60 °C

4: 91 percent / NaBH₄ / methanol; CH₂Cl₂ / 2 h

With sodium tetrahydroborate; hydroxylamine hydrochloride; potassium carbonate; triethylamine; In methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide;

DOI:10.1002/(SICI)1099-0682(199901)1999:1<179::AID-EJIC179>3.0.CO;2-5

Reference yield:

5-tert-butyl-2-(tert-butylthio)benzene-1,3-dialdehyde (220261-00-7) → N,N'-bis-<2-tert-butylsulfanyl-3-hydroximinomethyl-5-tert-butylbenzyl>propane-1,3-diamine (220261-03-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 69 percent / H₂N-OH*HCl, NEt₃ / CHCl₃ / 12 h

2: 93 percent / ethanol / 0.17 h / 60 °C

3: 91 percent / NaBH₄ / methanol; CH₂Cl₂ / 2 h

With sodium tetrahydroborate; hydroxylamine hydrochloride; triethylamine; In methanol; ethanol; dichloromethane; chloroform;

DOI:10.1002/(SICI)1099-0682(199901)1999:1<179::AID-EJIC179>3.0.CO;2-5

upstream raw materials:

2-bromo-5-tert-butyl-1,3-benzenedicarbaldehyde

5-tert-butyl-2-(tert-butylthio)benzene-1,3-dialdehyde

tert-butyl (4-tert-butyl-2-formyl-6-hydroximinomethylphenyl) sulfide