Technology Process of methyl 6-O-(6-O-acetyl-2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranosyl)-2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranoside
There total 10 articles about methyl 6-O-(6-O-acetyl-2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranosyl)-2-O-benzoyl-3,4-di-O-benzyl-β-D-galactopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 85 percent / triethylamine / 1 h / Ambient temperature
2: 97 percent / concd. H2SO4 / acetic acid / 8 h / 10 °C
3: 76 percent / HCl / diethyl ether / 48 h / Ambient temperature
4: methanol
5: 81.3 percent / acetonitrile / 17 h / Ambient temperature
6: 99 percent / ammonium hydroxide (32percent) / methanol / 8 h / Ambient temperature
7: 1.) silver p-toluenesulfonate / 1.) methanol; 2.) room temp., 17 h, acetonitrile
With
hydrogenchloride; ammonium hydroxide; sulfuric acid; silver(I) 4-methylbenzenesulfonate;
In
methanol; diethyl ether; acetic acid; triethylamine; acetonitrile;
DOI:10.1016/S0008-6215(00)85899-1
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 1.) sodium hydride / 1.) THF; 2.) reflux, 36 h
2: 93 percent / potassium tert-butoxide / toluene / 17 h / Heating
3: 56 percent / HCl (5percent) / dioxane / Heating
4: 85 percent / triethylamine / 1 h / Ambient temperature
5: 97 percent / concd. H2SO4 / acetic acid / 8 h / 10 °C
6: 76 percent / HCl / diethyl ether / 48 h / Ambient temperature
7: methanol
8: 81.3 percent / acetonitrile / 17 h / Ambient temperature
9: 99 percent / ammonium hydroxide (32percent) / methanol / 8 h / Ambient temperature
10: 1.) silver p-toluenesulfonate / 1.) methanol; 2.) room temp., 17 h, acetonitrile
With
hydrogenchloride; ammonium hydroxide; sulfuric acid; potassium tert-butylate; silver(I) 4-methylbenzenesulfonate; sodium hydride;
In
1,4-dioxane; methanol; diethyl ether; acetic acid; triethylamine; toluene; acetonitrile;
DOI:10.1016/S0008-6215(00)85899-1
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 97 percent / concd. H2SO4 / acetic acid / 8 h / 10 °C
2: 76 percent / HCl / diethyl ether / 48 h / Ambient temperature
3: methanol
4: 81.3 percent / acetonitrile / 17 h / Ambient temperature
5: 99 percent / ammonium hydroxide (32percent) / methanol / 8 h / Ambient temperature
6: 1.) silver p-toluenesulfonate / 1.) methanol; 2.) room temp., 17 h, acetonitrile
With
hydrogenchloride; ammonium hydroxide; sulfuric acid; silver(I) 4-methylbenzenesulfonate;
In
methanol; diethyl ether; acetic acid; acetonitrile;
DOI:10.1016/S0008-6215(00)85899-1
