C₁₈H₁₃F₃

Base Information

• Chemical Name: C₁₈H₁₃F₃
• CAS No.: 1254105-11-7
• Molecular Formula: C₁₈H₁₃F₃
• Molecular Weight: 286.296
• Mol file: 1254105-11-7.mol

Synonyms:C₁₈H₁₃F₃

Chemical Property of C₁₈H₁₃F₃

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₈H₁₃F₃

There total 6 articles about C₁₈H₁₃F₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

tri(n-butyl)(2-methyl-naphth-1-yl)stannane (110907-55-6) + 4-Iodobenzotrifluoride (455-13-0) → α,α,α-trifluorotoluene (98-08-8) + C18H13F3 (1254105-11-7)

Guidance literature:

With PdCl₂(AsPh₃)2; (triphenylarsine)gold(I) chloride; triphenyl-arsane; lithium chloride; In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.201209262

Reference yield: 68.0%

1-bromo-2-methylnaphtalene (2586-62-1) + 4-trifluoromethylphenylboronic acid (128796-39-4) → C18H13F3 (1254105-11-7)

Guidance literature:

With sodium tetrachloropalladate(II); 2-(1-(1-phenylethylamino)methyl)pyridine; In water; N,N-dimethyl-formamide; at 110 ℃; for 16h;

DOI:10.1016/j.tetlet.2010.07.151

Reference yield:

4-Iodobenzotrifluoride (455-13-0) + (2-methly-1-naphtyl)triethoxysilane → C18H13F3 (1254105-11-7)

Guidance literature:

With copper (II)-fluoride; [PdCl₂(1,3-dimethyl-imidazol-2-ylidene)(AsPh₃)]; In N,N-dimethyl-formamide; at 110 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1002/chem.201504435

upstream raw materials:

1-bromo-2-methylnaphtalene

4-trifluoromethylphenylboronic acid

tri(n-butyl)(2-methyl-naphth-1-yl)stannane

4-Iodobenzotrifluoride