1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile
CAS No.:517918-95-5
Molecular Formula:C8H5N3
Molecular Weight:143.148
Hs Code.:29339900
European Community (EC) Number:678-882-7
DSSTox Substance ID:DTXSID80472605
Nikkaji Number:J2.666.992H
Wikidata:Q72505572
Mol file:517918-95-5.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile;517918-95-5;5-Cyano-7-azaindole;MFCD06659684;7-Azaindole-5-carbonitrile;5-canyo-1H-Pyrrolo[2,3-b]pyridine;SCHEMBL298150;DTXSID80472605;DRAQIXNADYAISI-UHFFFAOYSA-N;BCP26452;CS-B0100;AKOS005258389;PB27739;DS-11118;SY003654;A7624;AM20070192;FT-0677980;A828778;A1-04836;J-517439;Boc-(S)-3-Amino-4-(2,4-dichlorophenyl)butanoicacid;1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, AldrichCPR;Z1198169610

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile
500mg
$ 110.00

SynQuest Laboratories
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile 97.0%
250 mg
$ 208.00

SynQuest Laboratories
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile 97.0%
1 g
$ 548.00

Sigma-Aldrich
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile Aldrich
1g
$ 637.00

Oakwood
5-Cyano-7-azaindole 98%
1g
$ 85.00

Matrix Scientific
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile 98%
1g
$ 84.00

Matrix Scientific
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile 98%
500mg
$ 55.00

Labseeker
5-Cyano-7-azaindole 95
5g
$ 462.00

Frontier Specialty Chemicals
5-Cyano-7-azaindole 98%
250mg
$ 92.00

Frontier Specialty Chemicals
5-Cyano-7-azaindole 98%
1g
$ 254.00

Total 71 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile

Chemical Property:

Melting Point:225.1-225.2 °C
PKA:12.50±0.40(Predicted)
PSA：52.47000
Density:1.34 g/cm³
LogP:1.43458
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:143.048347172
Heavy Atom Count:11
Complexity:193

Purity/Quality:

99%, ^*data from raw suppliers

1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22-36/37/38
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC2=NC=C(C=C21)C#N

Technology Process of 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile

There total 5 articles about 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 517918-95-5
1H-pyrrolo[2,3-b]pyridine-5-carbonitrile

Guidance literature:

Reference yield: 89.1%

: 557-21-1
zinc(II) cyanide

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 517918-95-5
1H-pyrrolo[2,3-b]pyridine-5-carbonitrile

Guidance literature:: With tetrakis-(triphenylphosphine)-palladium; In N,N-dimethyl-formamide; at 100 ℃; for 8h; Sealed tube; Inert atmosphere;
DOI:10.1016/j.bioorg.2021.105185