Technology Process of C26H21ClN6O5
There total 7 articles about C26H21ClN6O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C20H19N3O6;
With
tetrachloromethane;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
With
Hexamethylphosphorous triamide;
In
tetrahydrofuran; dichloromethane;
at -30 ℃;
for 0.166667h;
4-chloro-1H-pyrrolo[2,3-d]pyrimidine;
With
potassium tert-butylate;
In
tetrahydrofuran; dichloromethane;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium azide / acetone; water / 16 h / 50 °C
2.1: hydrogenchloride / ethanol / 5 h / 83 °C
3.1: dmap; triethylamine / acetonitrile / -10 °C
3.2: 20 °C
4.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / -30 °C
5.1: tetrachloromethane / tetrahydrofuran / 0.5 h / 20 °C
5.2: 0.17 h / -30 °C
5.3: 0 - 20 °C
With
hydrogenchloride; tetrachloromethane; dmap; sodium azide; lithium tri-t-butoxyaluminum hydride; triethylamine;
In
tetrahydrofuran; ethanol; water; acetone; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine; thionyl chloride / 25 °C
2.1: sodium azide / acetone; water / 16 h / 50 °C
3.1: hydrogenchloride / ethanol / 5 h / 83 °C
4.1: dmap; triethylamine / acetonitrile / -10 °C
4.2: 20 °C
5.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / -30 °C
6.1: tetrachloromethane / tetrahydrofuran / 0.5 h / 20 °C
6.2: 0.17 h / -30 °C
6.3: 0 - 20 °C
With
hydrogenchloride; tetrachloromethane; dmap; thionyl chloride; sodium azide; lithium tri-t-butoxyaluminum hydride; triethylamine;
In
tetrahydrofuran; ethanol; water; acetone; acetonitrile;
