5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one

Base Information

• Chemical Name: 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one
• CAS No.: 889110-22-9
• Molecular Formula: C₂₁H₁₉F₅OS₂
• Molecular Weight: 446.505
• Mol file: 889110-22-9.mol

Synonyms:5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one

Chemical Property of 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one

There total 2 articles about 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

C16H10F6S2 (889110-18-3) + pentan-3-one (96-22-0) → 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one (889110-22-9)

Guidance literature:

With potassium hydride; In tetrahydrofuran; at 0 ℃;

DOI:10.1055/s-2006-926352

Reference yield:

thiophenol (108-98-5) → 5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one (889110-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: TiCl₄ / CH₂Cl₂

1.2: 59 percent / aq. KOH; Bu₄NBr / CH₂Cl₂

2.1: 66 percent / KH / tetrahydrofuran / 0 °C

With titanium tetrachloride; potassium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1055/s-2006-926352

Reference yield: 63.0%

5-(Bis-phenylsulfanyl-methylene)-6,6,7,7,7-pentafluoro-4-methyl-heptan-3-one (889110-22-9) → 3-methyl-4-oxo-2-pentafluoroethyl-hexanethioic acid S-phenyl ester (889110-26-3)

Guidance literature:

With trifluoroacetic acid; Heating;

DOI:10.1055/s-2006-926352

upstream raw materials:

C₁₆H₁₀F₆S₂

pentan-3-one

thiophenol

Downstream raw materials:

3-methyl-4-oxo-2-pentafluoroethyl-hexanethioic acid S-phenyl ester