methyl (L)-N-allyl-N'-tosylallylglycinate

Base Information

Chemical Name:methyl (L)-N-allyl-N'-tosylallylglycinate
CAS No.:305836-74-2
Molecular Formula:C₁₆H₂₁NO₄S
Molecular Weight:323.413
Hs Code.:

Synonyms:methyl (L)-N-allyl-N'-tosylallylglycinate

Suppliers and Price of methyl (L)-N-allyl-N'-tosylallylglycinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (L)-N-allyl-N'-tosylallylglycinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (L)-N-allyl-N'-tosylallylglycinate

There total 4 articles about methyl (L)-N-allyl-N'-tosylallylglycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 106-95-6
allyl bromide

: 93267-06-2
(S)-2-(Toluene-4-sulfonylamino)pent-4-enoic acid methyl ester

: 305836-74-2
methyl (L)-N-allyl-N'-tosylallylglycinate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 10h;
DOI:10.1021/jo000898a

Reference yield:

: 16338-48-0
L-allylglycine

: 305836-74-2
methyl (L)-N-allyl-N'-tosylallylglycinate

Guidance literature:: Multi-step reaction with 3 steps

1.1: trimethylsilyl chloride; Et₃N / CH₂Cl₂ / 2 h / Heating

1.2: Et₃N / CH₂Cl₂ / 1 h / 20 °C

1.3: 79 percent / K₂CO₃; H₂O / methanol / pH 8

2.1: 95 percent / trimethylsilyl chloride / 7 h / Heating

3.1: 88 percent / K₂CO₃ / dimethylformamide / 10 h / 20 °C

With chloro-trimethyl-silane; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1.1: silylation / 1.2: Tosylation / 1.3: Hydrolysis / 2.1: Esterification / 3.1: Alkylation;
DOI:10.1021/jo000898a

Reference yield:

: 110579-31-2
(2S)-N-para-toluenesulfonylvinylglycine

: 305836-74-2
methyl (L)-N-allyl-N'-tosylallylglycinate

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / trimethylsilyl chloride / 7 h / Heating

2: 88 percent / K₂CO₃ / dimethylformamide / 10 h / 20 °C

With chloro-trimethyl-silane; potassium carbonate; In N,N-dimethyl-formamide; 1: Esterification / 2: Alkylation;
DOI:10.1021/jo000898a