10--decanoic acid

Base Information

• Chemical Name: 10--decanoic acid
• CAS No.: 175234-79-4
• Molecular Formula: C₃₁H₃₈O₅
• Molecular Weight: 490.64
• Mol file: 175234-79-4.mol

Synonyms:10--decanoic acid

Chemical Property of 10--decanoic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 10--decanoic acid

There total 4 articles about 10--decanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

10-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-decanoic acid methyl ester → 10--decanoic acid (175234-79-4)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 20 ℃; for 24h;

DOI:10.1093/nar/gkq853

Reference yield: 69.0%

10-hydroxydecanoic acid (1679-53-4) + 4,4'-dimethoxytrityl chloride (40615-36-9) → 10--decanoic acid (175234-79-4)

Guidance literature:

With pyridine; Ambient temperature;

DOI:10.1016/0040-4020(96)00018-X

Reference yield:

methyl 10-hydroxydecanoate (2640-94-0) → 10--decanoic acid (175234-79-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / DIPEA; DMAP / CH₂Cl₂

2: 65 percent / LiOH*H₂O / tetrahydrofuran; methanol; H₂O

With dmap; lithium hydroxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1021/ja027197a

upstream raw materials:

10-hydroxydecanoic acid

4,4'-dimethoxytrityl chloride

methyl 10-hydroxydecanoate