Technology Process of cis-3-Hydroxy-trans-4-tert.-butylcyclohexanol
There total 10 articles about cis-3-Hydroxy-trans-4-tert.-butylcyclohexanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetramethylammonium triacetoxyborohydride;
In
acetic acid; acetonitrile;
for 2h;
Ambient temperature;
DOI:10.1021/ja00219a035
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 82 percent / p-toluenesulfonic acid / 8 h / Ambient temperature
2: borane methyl sulfide / diethyl ether / 8 h / Ambient temperature
3: 81 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH2Cl2 / 14 h / Ambient temperature
4: L-Selectride / tetrahydrofuran / 4 h
5: 36 percent / 50percent aq. acetic acid / tetrahydrofuran / 6 h / Ambient temperature
6: 86 percent / tetramethylammonium triacetoxyborohydride / acetonitrile; acetic acid / 2 h / Ambient temperature
With
dipyridinium dichromate; dimethylsulfide borane complex; pyridinium trifluroacetate; L-Selectride; acetic acid; tetramethylammonium triacetoxyborohydride;
toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; acetic acid; acetonitrile;
DOI:10.1021/ja00219a035
- Guidance literature:
-
Multi-step reaction with 5 steps
1: borane methyl sulfide / diethyl ether / 8 h / Ambient temperature
2: 81 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH2Cl2 / 14 h / Ambient temperature
3: L-Selectride / tetrahydrofuran / 4 h
4: 36 percent / 50percent aq. acetic acid / tetrahydrofuran / 6 h / Ambient temperature
5: 86 percent / tetramethylammonium triacetoxyborohydride / acetonitrile; acetic acid / 2 h / Ambient temperature
With
dipyridinium dichromate; dimethylsulfide borane complex; pyridinium trifluroacetate; L-Selectride; acetic acid; tetramethylammonium triacetoxyborohydride;
In
tetrahydrofuran; diethyl ether; dichloromethane; acetic acid; acetonitrile;
DOI:10.1021/ja00219a035
