Technology Process of C15H22O4
There total 4 articles about C15H22O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
osmium(VIII) oxide; N,N,N,N,-tetramethylethylenediamine;
In
dichloromethane;
at -78 ℃;
for 14h;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/ol3007259
- Guidance literature:
-
Multi-step reaction with 3 steps
1: methanol; lithium borohydride / diethyl ether / 0 - 20 °C
2: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 °C / Inert atmosphere
3: osmium(VIII) oxide; N,N,N,N,-tetramethylethylenediamine / dichloromethane / 14 h / -78 °C / Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; methanol; osmium(VIII) oxide; lithium borohydride; N,N,N,N,-tetramethylethylenediamine;
In
diethyl ether; dichloromethane;
DOI:10.1021/ol3007259
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 °C / Inert atmosphere
2: osmium(VIII) oxide; N,N,N,N,-tetramethylethylenediamine / dichloromethane / 14 h / -78 °C / Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; osmium(VIII) oxide; N,N,N,N,-tetramethylethylenediamine;
In
dichloromethane;
DOI:10.1021/ol3007259
