4-Boc-1-piperazinecarbonyl Chloride

Base Information

Chemical Name:4-Boc-1-piperazinecarbonyl Chloride
CAS No.:59878-28-3
Molecular Formula:C10H17 Cl N2 O3
Molecular Weight:248.71
Hs Code.:2933599590
European Community (EC) Number:861-093-9
DSSTox Substance ID:DTXSID50462710
Wikidata:Q82287290
Mol file:59878-28-3.mol

Synonyms:59878-28-3;4-Boc-1-piperazinecarbonyl Chloride;Tert-butyl 4-carbonochloridoylpiperazine-1-carboxylate;tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate;4-chlorocarbonyl-piperazine-1-carboxylic acid tert-butyl ester;Tert-butyl 4-(carbonochloridoyl)piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-(chlorocarbonyl)-, 1,1-dimethylethyl ester;MFCD09028534;4-Boc-1-piperazinecarbonylChloride;tert-butyl 4-chlorocarbonyl-1-piperazinecarboxylate;tert-butyl 4-chlorocarbonylpiperazine-1-carboxylate;SCHEMBL485772;DTXSID50462710;NCIQNWYJLAAFAH-UHFFFAOYSA-N;1-Boc-4-(chlorocarbonyl)piperazine;AB6598;ZH0021;AKOS024257464;SB11269;AS-44783;SY024237;EN300-155336;tert-butyl 4-(carboxy)piperazine-1-carboxylate;1-chlorocarbonyl-4-tert-butoxycarbonylpiperazine;4-tert-butoxycarbonyl-1-chlorocarbonylpiperazine;A857310;tert-Butyl 4-chlorocarbonyl-piperazine-1-carboxylate;tert-Butyl 4-chlorocarbonyl-piperazine-1 -carboxylate;4-(2-methyl-2-propyloxycarbonyl)piperazine-1-carbonylchloride

Suppliers and Price of 4-Boc-1-piperazinecarbonyl Chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Piperazinecarboxylicacid
1g
$ 594.00

Crysdot
4-Boc-1-piperazinecarbonylChloride 95+%
1g
$ 190.00

Crysdot
4-Boc-1-piperazinecarbonylChloride 95+%
5g
$ 460.00

Chemenu
4-Boc-1-piperazinecarbonylChloride 95%
10g
$ 489.00

Chemenu
4-Boc-1-piperazinecarbonylChloride 95%
5g
$ 294.00

American Custom Chemicals Corporation
4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 499.93

Alichem
4-Boc-1-piperazinecarbonylChloride
10g
$ 543.92

Alichem
4-Boc-1-piperazinecarbonylChloride
5g
$ 332.84

AK Scientific
Tert-butyl4-(carbonochloridoyl)piperazine-1-carboxylate
10g
$ 744.00

Absolute Chiral
tert-butyl4-chlorocarbonylpiperazine-1-carboxylate 95%
100 mg
$ 98.00

Total 34 raw suppliers

Chemical Property of 4-Boc-1-piperazinecarbonyl Chloride

Chemical Property:

Boiling Point:354.5±31.0 °C(Predicted)
PKA:-0.41±0.70(Predicted)
PSA：49.85000
Density:1.231±0.06 g/cm3(Predicted)
LogP:1.77370
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:248.0927701
Heavy Atom Count:16
Complexity:280

Purity/Quality:

99%, ^*data from raw suppliers

1-Piperazinecarboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCN(CC1)C(=O)Cl

Technology Process of 4-Boc-1-piperazinecarbonyl Chloride

There total 7 articles about 4-Boc-1-piperazinecarbonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 59878-28-3
tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

Reference yield: 89.0%

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 59878-28-3
tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

Guidance literature:: With pyridine; bis(trichloromethyl) carbonate; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

: carbonic acid trichloromethyl ester

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 59878-28-3
tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate

Guidance literature:: carbonic acid trichloromethyl ester; 1-t-Butoxycarbonylpiperazine; With pyridine; In dichloromethane; at 0 - 20 ℃; for 2h;

With hydrogenchloride; In dichloromethane; water;