3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose

Base Information

• Chemical Name: 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose
• CAS No.: 130222-70-7
• Molecular Formula: C₁₈H₂₅O₇P
• Molecular Weight: 384.366
• Mol file: 130222-70-7.mol

Synonyms:3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose

Chemical Property of 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose

There total 2 articles about 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

[1-((3aR,5S,6R,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-nitro-ethyl]-phosphonic acid dimethyl ester (113713-83-0,113713-85-2,130320-73-9,141782-03-8,141782-04-9) → 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose (130222-70-7)

Guidance literature:

With sodium methylate; In methanol; for 8h; Heating;

DOI:10.1055/s-1990-26893

Reference yield: 72.0%

3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-6-nitro-α-D-xylo-hex-5-enofuranose (69177-83-9,78283-50-8,86495-59-2,114181-97-4,141782-01-6,51173-35-4) → 3-O-benzyl-5,6-dideoxy-5-C-(dimethoxyphosphinyl)-1,2-O-isopropylidene-α-D-xylo-hexo-5-enofuranose (130222-70-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; at 20 ℃; for 3h;

DOI:10.1246/bcsj.66.2315

upstream raw materials:

[1-((3aR,5S,6R,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-nitro-ethyl]-phosphonic acid dimethyl ester

3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-6-nitro-α-D-xylo-hex-5-enofuranose